Department of Medicine (Division of Gastroenterology) and Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton Ontario, Canada.
J Gastroenterol Hepatol. 2010 Dec;25(12):1827-30. doi: 10.1111/j.1440-1746.2010.06444.x.
Patients with diverticular disease may experience a variety of chronic symptoms, including abdominal discomfort, bloating, and altered bowel habit. They are also at risk of complications, including hemorrhage, diverticulitis, abscess, and fistula formation. The potential role of abnormal colonic microflora in the pathogenesis of diverticular inflammation has led to investigation of novel therapies such as probiotics. Probiotics are microorganisms that may be of net benefit to humans when consumed. The rationale and safety of their use in diverticular disease is discussed and current literature is reviewed.
患有憩室病的患者可能会出现各种慢性症状,包括腹部不适、腹胀和排便习惯改变。他们也有发生并发症的风险,包括出血、憩室炎、脓肿和瘘管形成。异常结肠微生物群在憩室炎发病机制中的潜在作用促使人们研究新型治疗方法,如益生菌。益生菌是当被消耗时可能对人类有净益处的微生物。本文讨论了其在憩室病中的应用的原理和安全性,并对当前的文献进行了回顾。