Majcher Anna, Pyrżak Beata, Bielecka-Jasiocha Joanna, Witkowska-Sędek Ewelina
Klinika Pediatrii i Endokrynologii WUM.
Pediatr Endocrinol Diabetes Metab. 2010;16(3):148-52.
Birth parameters are one of the more important predictors of body height in adult life. Children with low birth weight (LBW) are an essential and heterogenic group of patients diagnosed because of short stature.
Evaluation of frequency of low birth mass in children with short stature and evaluation of anthropometric parameters in children with low and normal birth weight.
Analysis of birth data and present somatic parameters in 802 children with short stature who were admitted to the Clinic of Paediatrics and Endocrinology. This group consisted of 456 boys and 346 girls. The mean calendar age was 9 years. Differential diagnosis of growth disorders was made. Our group contained 133 children with growth hormone deficiency (GHD) and 26 girls with Turner's syndrome. Data of birth parameters (length, weight and length of pregnancy) were collected, anthropometric measurements of children and their parents were made, body mass index (BMI) was calculated. Low birth weight (LBW) is a birth weight ≤2500 g. The values of present somatic parameters were normalized according to the references of the Institute of Mother and Child, data of parameters were given in standard deviation score.
In the whole examined group LBW was observed in 17.3% (137 children). LBW was observed in 23% of girls with Turner's syndrome. Among the children who were born on time low birth weight was observed in 5.3% (30 children--15 boys and 15 girls). In this group there were 10 patients from a twin pregnancy, 2 with fetal alcohol syndrome and 4 with Silver-Russell syndrome. In 14 patients SGA (small for gestational age) was observed. The children with LBW contacted the clinic a year earlier than other patients, with more body height deficiency (-2.5 SDS vs. -2.1 SDS) and smaller values of BMI. No statistically significant differences between midparental height in both groups were observed.
出生参数是成年后身高的重要预测指标之一。低出生体重（LBW）儿童是因身材矮小而被诊断出的一个重要且异质性的患者群体。
评估身材矮小儿童中低出生体重的发生率，并评估低出生体重和正常出生体重儿童的人体测量参数。
对802名入住儿科和内分泌科诊所的身材矮小儿童的出生数据和当前身体参数进行分析。该组包括456名男孩和346名女孩。平均年龄为9岁。对生长障碍进行了鉴别诊断。我们的组中有133名生长激素缺乏（GHD）儿童和26名特纳综合征女孩。收集了出生参数（身长、体重和孕期长度）数据，对儿童及其父母进行了人体测量，并计算了体重指数（BMI）。低出生体重是指出生体重≤2500克。根据母婴研究所的参考标准对当前身体参数值进行了标准化，参数数据以标准差分数给出。
在整个检查组中，观察到17.3%（137名儿童）为低出生体重。特纳综合征女孩中有23%为低出生体重。在足月出生的儿童中，观察到5.3%（30名儿童——15名男孩和15名女孩）为低出生体重。该组中有10名来自双胎妊娠的患者，2名患有胎儿酒精综合征，4名患有Silver-Russell综合征。在14名患者中观察到小于胎龄儿（SGA）。低出生体重儿童比其他患者提前一年就诊，身高缺陷更大（-2.5 SDS对-2.1 SDS），BMI值更小。两组中父母身高中位数之间未观察到统计学上的显著差异。
