Bonzano L, Colombino G, Petri G, Vittone L, Barbera C, Manzoni R
U.S.S.L. n. 47, Ospedale degli Infermi, Biella (Vercelli).
Minerva Med. 1990 Mar;81(3 Suppl):49-51.
We describe a 7-years boy by with a meningococcal sepsis due to Neisseria Meningitidis, with very serious evolution of cutaneous necrosis, initial D.I.C. and heart failure. The clinical picture do not improve with antibiotic therapy (CAF-penicillin), but the association ceftriaxone + tobramycin results in rapid improvement. The cutaneous necrosis, especially evident on gluteus, arms and legs, were treated locally with AgNO3 and penicillin-solution. After 4 weeks of treatment, also this cutaneous involvement improved and now the boy is healthy, without residual signs neither systemic nor cutaneous.
我们描述了一名7岁男孩,因脑膜炎奈瑟菌感染患脑膜炎球菌败血症,伴有皮肤坏死、最初的弥散性血管内凝血和心力衰竭的非常严重的病情进展。抗生素治疗(头孢氨苄-青霉素)后临床症状未改善,但头孢曲松+妥布霉素联合使用导致病情迅速改善。皮肤坏死在臀部、手臂和腿部尤为明显,局部用硝酸银和青霉素溶液治疗。治疗4周后,皮肤受累情况也有所改善,现在男孩很健康,没有全身或皮肤的残留体征。