Madle-Samardzija N, Dimić E, Vukadinov J, Jovanović J, Celanović M, Malenković M, Canak G, Preveden T, Brkić S
Klinika za infektivne i dermatoveneroloske bolesti, Medicinski fakultet, Novi Sad.
Med Pregl. 1993;46(5-6):188-90.
We report a case of meningococcal sepsis in a healthy immunocompetent sixteen year old boy who had developed upper respiratory tract acute infection 10 days before the admittance. Clinical manifestations were similar to those found in allergic hemorrhagic purpura (Schonlein's form of the disease). The clinical course of these two diseases is usually different but sometimes they cannot be easily differentiated. The acute onset of polyarthritis, temperature and skin manifestations in the form of erythematous maculopapular exanthema which within several hours evolved into hemorrhagic purpura is typical for the sepsis caused by Neisseria meningitides but these characteristics might be found in allergic Henoch-Schonlein' purpura as well. In our case the accurate diagnosis was set by the identification of the group C Neisseriae meningitides from the patient's blood. The first choice was penicillin therapy.
我们报告一例16岁健康免疫功能正常男孩的脑膜炎球菌败血症病例，该男孩在入院前10天出现上呼吸道急性感染。临床表现与过敏性出血性紫癜（ Schönlein型疾病）相似。这两种疾病的临床病程通常不同，但有时不易区分。多关节炎、发热以及皮肤表现为红斑丘疹性皮疹并在数小时内演变为出血性紫癜的急性发作是脑膜炎奈瑟菌败血症的典型表现，但这些特征在过敏性亨诺赫-舍恩莱因紫癜中也可能出现。在我们的病例中，通过从患者血液中鉴定出C群脑膜炎奈瑟菌得以明确诊断。首选治疗药物为青霉素。
