Laboratory of Histology & Embryology, Medical School, Aristotle University of Thessaloniki, Greece.
Placenta. 2011 Jan;32(1):102-4. doi: 10.1016/j.placenta.2010.10.013. Epub 2010 Nov 18.
Chorangioma is the most common non-trophoblastic tumor of the placenta, which represents an excessive vascular proliferation within chorionic villi. While the histologic picture of a chorangioma may vary greatly from lesion to lesion, the presence of abundant smooth muscle tissue within a chorangioma has not been previously reported. Herein we report a case of a 34-year-old primigravida woman with a peculiar mesenchymal placental tumor, characterized by combined features of chorangioma and leiomyoma; large lobules of numerous small blood vessels within loose stroma, separated by broad bundles of smooth muscle fibers. Genetic studies by means of PCR excluded maternal and confirmed placental origin of the lesion.
绒毛血管瘤是胎盘最常见的非滋养层肿瘤，代表绒毛内血管过度增殖。虽然绒毛血管瘤的组织学表现可能因病变而异，但绒毛血管瘤内存在丰富的平滑肌组织以前尚未报道过。在此，我们报告一例 34 岁初产妇的特殊间质性胎盘肿瘤，其特征为绒毛血管瘤和平滑肌瘤的特征相结合；疏松基质内有大量小血管的大小叶，由宽阔的平滑肌纤维束分隔。通过 PCR 进行的遗传研究排除了母体并证实了病变的胎盘来源。
