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恶性胎盘部位滋养细胞肿瘤

Malignant placental site trophoblastic tumor.

作者信息

Hopkins M, Nunez C, Murphy J R, Wentz W B

出版信息

Obstet Gynecol. 1985 Sep;66(3 Suppl):95S-100S.

PMID:2991836
Abstract

Placental site trophoblastic tumor is a rare variant of trophoblastic disease. The malignant form of this disease with metastasis and death is even more infrequent, as is evident from only five cases in the literature. A 30-year-old black woman who died from this disease is presented. Patients with metastases are at extremely high risk with no reported survivors and must be treated aggressively with chemotherapy and cytoreductive surgery. This type of trophoblastic tumor apparently exhibits a different biologic behavior as compared with choriocarcinoma.

摘要

胎盘部位滋养细胞肿瘤是滋养细胞疾病的一种罕见类型。这种具有转移和致死性的恶性疾病更为少见,文献中仅有5例报道可资证明。本文报告了一名死于该疾病的30岁黑人女性。发生转移的患者处于极高风险,尚无幸存者报道,必须积极采用化疗和减瘤手术进行治疗。与绒毛膜癌相比,这种类型的滋养细胞肿瘤显然表现出不同的生物学行为。

相似文献

1
Malignant placental site trophoblastic tumor.恶性胎盘部位滋养细胞肿瘤
Obstet Gynecol. 1985 Sep;66(3 Suppl):95S-100S.
2
Malignant placental site trophoblastic tumor. A case report and a review of the literature.恶性胎盘部位滋养细胞肿瘤。病例报告及文献复习。
APMIS Suppl. 1991;23:138-45.
3
Clinical experience with placental site trophoblastic tumors at the New England Trophoblastic Disease Center.
Obstet Gynecol. 1988 Jun;71(6 Pt 1):854-7.
4
Placental site trophoblastic tumor: an overview.胎盘部位滋养细胞肿瘤:概述
J Reprod Med. 2004 Aug;49(8):585-8.
5
[Placental site trophoblastic tumor. A case report with immunohistochemical and ultrastructural studies].[胎盘部位滋养细胞肿瘤。一例免疫组织化学和超微结构研究的病例报告]
Pathologe. 1989 Nov;10(6):359-63.
6
[Trophoblastic tumor at the site of placental implantation. Apropos of a new case].胎盘植入部位的滋养细胞肿瘤。关于一例新病例
J Gynecol Obstet Biol Reprod (Paris). 1988;17(2):201-6.
7
Non-trophoblastic tumor of the placenta with combined histologic features of chorangioma and leiomyoma.胎盘非滋养细胞肿瘤,具有绒毛膜血管瘤和平滑肌瘤的组织学特征。
Placenta. 2011 Jan;32(1):102-4. doi: 10.1016/j.placenta.2010.10.013. Epub 2010 Nov 18.
8
Clinical and laboratory investigation of a virilized woman with placental-site trophoblastic tumor.一名患胎盘部位滋养细胞肿瘤的男性化女性的临床及实验室检查
Obstet Gynecol. 1985 Apr;65(4):527-34.
9
Chemotherapy for trophoblastic disease: current standards.
Expert Rev Anticancer Ther. 2003 Feb;3(1):48-54. doi: 10.1586/14737140.3.1.48.
10
Placental-site trophoblastic tumor (trophoblastic pseudotumor): case report demonstrating failure of chemotherapy, surgery, and radiotherapy to control metastatic disease.胎盘部位滋养细胞肿瘤(滋养细胞假瘤):病例报告显示化疗、手术及放疗均无法控制转移性疾病。
Gynecol Oncol. 1985 May;21(1):111-7. doi: 10.1016/0090-8258(85)90241-0.

引用本文的文献

1
Placental site trophoblastic tumor.胎盘部位滋养细胞肿瘤
J Cancer Res Clin Oncol. 2008 Jan;134(1):1-6. doi: 10.1007/s00432-007-0208-y. Epub 2007 Aug 16.
2
Long term remission of metastatic placental site trophoblastic tumor (PSTT): Case report and review of literature.转移性胎盘部位滋养细胞肿瘤(PSTT)的长期缓解:病例报告及文献综述
World J Surg Oncol. 2005 Jun 15;3(1):34. doi: 10.1186/1477-7819-3-34.
3
Placental site trophoblastic tumour: a rare but potentially curable cancer.胎盘部位滋养细胞肿瘤:一种罕见但有可能治愈的癌症。
Br J Cancer. 2000 Mar;82(6):1186-90. doi: 10.1054/bjoc.1999.1061.