儿童过敏性紫癜合并格林-巴利综合征。

Henoch-Schönlein purpura in a child with Guillain-Barré syndrome.

机构信息

Department of General Pediatrics, Nihon University Nerima Hikarigaoka Hospital, Nihon University School of Medicine, Tokyo, Japan.

出版信息

Pediatr Neurol. 2010 Dec;43(6):431-4. doi: 10.1016/j.pediatrneurol.2010.06.008.

DOI:10.1016/j.pediatrneurol.2010.06.008

PMID:21093736

Abstract

A case of Henoch-Schönlein purpura with Guillain-Barré syndrome in a 3-year-old-girl is presented. This association is extremely rare. During the course of Guillain-Barré syndrome, a decrease in plasma factor XIII activity was noted. When the Guillain-Barré symptoms improved, the factor XIII activity returned to normal. In the present case of Henoch-Schönlein purpura complicated by Guillain-Barré syndrome, the factor XIII level was measured, a novel feature of this study. The findings suggest the involvement of factor XIII, which is characteristically involved in Henoch-Schönlein purpura, also is involved in the associated Guillain-Barré syndrome.

摘要

现报道 1 例 3 岁女孩患过敏性紫癜合并格林-巴利综合征病例。这种关联极为罕见。在格林-巴利综合征的病程中，发现血浆因子 XIII 活性降低。当格林-巴利症状改善时，因子 XIII 活性恢复正常。在本病例中，过敏性紫癜并发格林-巴利综合征，测定了因子 XIII 水平，这是本研究的一个新特征。研究结果提示，在典型的过敏性紫癜中起作用的因子 XIII 也参与了相关的格林-巴利综合征。