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[人类听觉系统探索:从短声到言语听觉脑干反应]

[Exploration of the auditory system in humans: From click to speech auditory brainstem responses].

作者信息

Richard C, Jeanvoine A, Veuillet E, Moulin A, Thai-Van H

机构信息

UMR CNRS 5020, laboratoire neurosciences sensorielles, comportement, cognition, hôpital Édouard-Herriot, université de Lyon, université Lyon 1, 5, place d'Arsonval, 69437 Lyon cedex 03, France.

出版信息

Neurophysiol Clin. 2010 Nov-Dec;40(5-6):267-79. doi: 10.1016/j.neucli.2010.08.002. Epub 2010 Oct 1.

Abstract

There is a growing and unprecedented interest in the objective evaluation of the subcortical processes that are involved in speech perception, with potential clinical applications in speech and language impairments. Here, we review the studies illustrating the development of electrophysiological methods for assessing speech encoding in the human brainstem: from the pioneer recordings of click-evoked auditory brainstem responses (ABR), via studies of frequency-following responses (FFR) to the most recent measurements of speech ABR (SABR) or ABR in response to speech sounds. Recent research on SABR has provided new insights in the understanding of subcortical auditory processing mechanisms. The SABR test is an objective and non-invasive tool for assessing individual capacity of speech encoding in the brainstem. SABR characteristics are potentially useful both as a diagnosis tool of speech encoding deficits and as an assessment tool of the efficacy of rehabilitation programs in patients with learning and/or auditory processing disorders.

摘要

人们对参与言语感知的皮层下过程的客观评估兴趣日益浓厚,且这种兴趣前所未有的高涨,这在言语和语言障碍方面具有潜在的临床应用价值。在此,我们回顾一些研究,这些研究阐述了评估人类脑干言语编码的电生理方法的发展历程:从最初记录点击诱发的听觉脑干反应(ABR),到对频率跟随反应(FFR)的研究,再到最近对言语ABR(SABR)或对语音声音反应的ABR的测量。最近关于SABR的研究为理解皮层下听觉处理机制提供了新的见解。SABR测试是一种客观且非侵入性的工具,用于评估个体在脑干中进行言语编码的能力。SABR特征作为言语编码缺陷的诊断工具以及学习和/或听觉处理障碍患者康复计划疗效的评估工具,都具有潜在的用途。

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