Division of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2010 Nov;73(11):596-8. doi: 10.1016/S1726-4901(10)70129-5.
New Delhi metallo-β-lactamase 1 (NDM-1) is a novel type of metallo-β-lactamase (MBL). Enterobacteriaceae carrying this NDM-1 encoding gene, bla(NDM-1), have been identified worldwide. Bacteria carrying bla(NDM-1) are not only resistant to carbapenem, but also highly resistant to many classes of antibiotics, which indicate the importance of prompt identification of these bacteria and implementation of strict infection control measures to prevent their transmission. Here, we report the first identification and management of a patient colonized with Klebsiella pneumoniae carrying bla(NDM-1) in Taiwan, who returned from New Delhi where he had been hospitalized for a gun-shot injury.
新德里金属β-内酰胺酶 1（NDM-1）是一种新型金属β-内酰胺酶（MBL）。已在全球范围内发现携带这种编码基因 bla（NDM-1）的肠杆菌科细菌。携带 bla（NDM-1）的细菌不仅对碳青霉烯类抗生素具有耐药性，而且对许多类别的抗生素也具有高度耐药性，这表明及时鉴定这些细菌并实施严格的感染控制措施以防止其传播非常重要。在这里，我们报告了在台湾首次发现并管理一名携带 bla（NDM-1）的肺炎克雷伯菌定植患者的情况，该患者从新德里返回，他曾在新德里因枪伤住院。
