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从储存在UW溶液中6至26小时的人胰腺中分离胰岛。

Islet isolation from human pancreas stored in UW solution for 6 to 26 hours.

作者信息

Kneteman N M, Warnock G L, Evans M G, Dawidson I, Rajotte R V

机构信息

Department of Surgery, University of Alberta, Edmonton, Canada.

出版信息

Transplant Proc. 1990 Apr;22(2):763-4.

PMID:2109396
Abstract
  1. Viable and functional islets can be recovered from human pancreata stored for prolonged periods (up to 18 hours) with either the UW solution or EC. 2. Function of islets from pancreas stored in UW solution appeared superior. However, the difference in these preliminary studies does not appear nearly so dramatic as in transplantation of vascularized pancreas. 3. Function of islets from human pancreas stored for longer than 18 hours after UW in situ flush was uniformly poor. 4. Considerable room for improvement in the storage of human pancreas before isolation exists. Progress in this area will be important for the development of any large-scale program of clinical islet transplantation.
摘要
  1. 用UW溶液或EC溶液可从长时间(长达18小时)保存的人胰腺中回收有活力且功能正常的胰岛。2. 保存在UW溶液中的胰腺所分离出的胰岛功能似乎更优。然而,这些初步研究中的差异远不如在血管化胰腺移植中那么显著。3. UW原位冲洗后保存超过18小时的人胰腺所分离出的胰岛功能均较差。4. 在胰岛分离前,人胰腺的保存仍有很大的改进空间。这一领域的进展对于任何大规模临床胰岛移植项目的开展都至关重要。

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Islet isolation from human pancreas stored in UW solution for 6 to 26 hours.从储存在UW溶液中6至26小时的人胰腺中分离胰岛。
Transplant Proc. 1990 Apr;22(2):763-4.
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Metabolites. 2022 Dec 15;12(12):1270. doi: 10.3390/metabo12121270.
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Hypothermic storage and preservation of human pancreatic acinar tissue.
In Vitro Cell Dev Biol Anim. 2007 Jan;43(1):2-6. doi: 10.1007/s11626-006-9006-0.