Duval Renaud, Hammamji Karim, Aroichane Maryam, Michaud Jacques L, Ospina Luis H
Department of Pediatric Ophthalmology, Le Centre Hospitalier Universitaire Mère-Enfant Sainte-Justine, University of Montreal, Montreal, Canada.
J AAPOS. 2010 Dec;14(6):544-7. doi: 10.1016/j.jaapos.2010.08.008. Epub 2010 Nov 19.
Myelinated retinal nerve fibers are a well-recognized anomaly of the ocular fundus associated with many ocular and systemic conditions. Myelination is almost always congenital and stable, but progression has been documented in rare cases. Optic disk drusen are the result of a degenerative process at the optic nerve head and are often found incidentally on ophthalmologic examination. To our knowledge, optic disk drusen have only been reported once in association with acquired and progressive myelinated retinal nerve fibers. We present 2 such cases and consider the implications for the pathogenesis of myelinated nerve fibers.
有髓神经纤维是一种公认的眼底异常，与许多眼部和全身疾病相关。髓鞘形成几乎总是先天性的且稳定，但在罕见情况下也有进展的记录。视盘玻璃疣是视神经乳头退行性变的结果，常在眼科检查时偶然发现。据我们所知，视盘玻璃疣仅在1例后天性进行性有髓神经纤维病例中被报道过。我们报告2例此类病例，并探讨其对有髓神经纤维发病机制的意义。
