Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Semin Perinatol. 2010 Dec;34(6):426-33. doi: 10.1053/j.semperi.2010.09.007.
Hypothermia among newborns is considered an important contributor to neonatal morbidity and mortality in low-resource settings. However, in these settings only limited progress has been made towards understanding the risk of mortality after hypothermia, describing how this relationship is dependent on both the degree or severity of exposure and the gestational age and weight status of the baby, and implementing interventions to mitigate both exposure and the associated risk of poor outcomes. Given the centrality of averting neonatal mortality to achieving global milestones towards reductions in child mortality by 2015, recent years have seen substantial resources and efforts implemented to improve understanding of global epidemiology of neonatal health. In this article, a summary of the burden, consequences, and risk factors of neonatal hypothermia in low-resources settings is presented, with a particular focus on community-based data. Context-appropriate interventions for reducing hypothermia exposure and the role of these interventions in reducing global neonatal mortality burden are explored.
在资源匮乏的环境中,新生儿低体温被认为是导致新生儿发病率和死亡率的一个重要因素。然而,在这些环境中,人们对于新生儿低体温后死亡率的风险的理解仅取得了有限的进展,还不能描述这种关系如何取决于暴露的程度或严重程度以及婴儿的胎龄和体重状况,并实施干预措施来减轻暴露和不良后果的相关风险。鉴于避免新生儿死亡对于实现全球减少儿童死亡率的目标至关重要,近年来已经投入了大量资源和精力来提高对全球新生儿健康流行病学的认识。本文总结了资源匮乏环境中新生儿低体温的负担、后果和危险因素,特别关注基于社区的数据。本文还探讨了减少低体温暴露的适宜干预措施以及这些干预措施在降低全球新生儿死亡负担方面的作用。