Department of Epidemiology and Biostatistics, University of Florida, Gainesville, Florida 32610, USA.
J Adolesc Health. 2010 Dec;47(6):596-9. doi: 10.1016/j.jadohealth.2010.09.015.
To determine age- and race-specific uptake rates of human papillomavirus (HPV) vaccine among females aged 9-20 years who participated in the Florida Medicaid during the first 2 years after approval by the Food and Drug Administration, and to identify factors associated with HPV vaccine initiation and series completion.
Medicaid administrative data were used to identify claims for HPV vaccination together with individual, provider, and practice characteristics linked to each vaccination.
As of June 2008, 9.4% of females aged 11-18 years had ever received an HPV vaccination, and 1.8% had completed the three-vaccine series. In multivariate analysis, receipt of an HPV vaccination was found to be associated with age and race/ethnicity. In comparison with their white counterparts, black females were approximately half as likely to complete the three-vaccine series after initiation.
The data obtained suggest relatively slow initial uptake and completion of the HPV vaccine series in this population who are at an increased risk for cervical cancer, with racial disparities in vaccine uptake and vaccine series completion.
在食品和药物管理局批准后最初的 2 年内,确定参加佛罗里达州医疗补助计划的 9-20 岁女性中 HPV 疫苗的年龄和种族特异性接种率,并确定与 HPV 疫苗接种启动和系列完成相关的因素。
使用医疗补助管理数据来识别 HPV 疫苗接种的索赔,以及与每次接种相关的个人、提供者和实践特征。
截至 2008 年 6 月,11-18 岁的女性中,有 9.4%的人曾经接种过 HPV 疫苗,1.8%的人完成了三剂疫苗系列。在多变量分析中,HPV 疫苗的接种与年龄和种族/族裔有关。与白人相比,黑人女性在开始接种后完成三剂疫苗系列的可能性约为其一半。
从所获得的数据来看,在宫颈癌风险增加的人群中,HPV 疫苗的初始接种和完成率相对较低,并且在疫苗接种和疫苗系列完成方面存在种族差异。