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女大学生接种人乳头瘤病毒疫苗与 HPV 知识和风险认知有关吗?

Is use of the human papillomavirus vaccine among female college students related to human papillomavirus knowledge and risk perception?

机构信息

Roswell Park Cancer Institute, Elm and Carlton, Buffalo, New York 14263, USA.

出版信息

Sex Transm Infect. 2010 Feb;86(1):74-8. doi: 10.1136/sti.2009.037705. Epub 2009 Oct 19.

Abstract

BACKGROUND

Few studies have examined factors associated with the actual use of the human papillomavirus (HPV) vaccine since licensure in 2006. The aims of this study were to assess HPV vaccination rates and to examine whether knowledge and risk perceptions regarding HPV were associated with the reported use of the HPV vaccine among female college students.

METHODS

Using a cross-sectional design, 406 women aged 18-26 years were recruited at two public universities and completed a self-administered survey. Respondents who reported having received at least one dose of HPV vaccine were classified as 'vaccinated' (n=177, 43.6%). Responses, stratified by the receipt of HPV vaccine, were compared using descriptive statistics and multivariate models.

RESULTS

Based on multivariate logistic regression modelling, 18-year-old women were approximately four times more likely to report use of the HPV vaccine compared with respondents aged 19-26 years. Respondents who correctly indicated that HPV caused genital warts were 1.85 times more likely (adjusted odds ratio (OR) 1.85, 95% CI 1.20 to 2.93) to have received at least one HPV vaccine. African American and Asian women were each less likely to be vaccinated compared with white women. Risk perception was not significantly associated with vaccine uptake, however, the majority of respondents failed accurately to recognise their high risk of both acquiring and transmitting HPV.

CONCLUSIONS

These findings suggest knowledge deficits and misperceptions about HPV risk as potential themes for educational campaigns encouraging the greater use of the preventive HPV vaccine among this subgroup.

摘要

背景

自 2006 年 HPV 疫苗获得许可以来,很少有研究调查与实际使用 HPV 疫苗相关的因素。本研究旨在评估 HPV 疫苗接种率,并检验女性大学生报告的 HPV 相关知识和风险认知是否与 HPV 疫苗的使用有关。

方法

采用横断面设计,在两所公立大学招募了 406 名 18-26 岁的女性,她们完成了一份自我管理的调查。将报告至少接种过一剂 HPV 疫苗的受访者归类为“已接种”(n=177,43.6%)。使用描述性统计和多变量模型比较按 HPV 疫苗接种情况分层的应答。

结果

基于多变量逻辑回归模型,18 岁的女性报告使用 HPV 疫苗的可能性大约是 19-26 岁女性的四倍。正确指出 HPV 会引起生殖器疣的受访者接种 HPV 疫苗的可能性高出 1.85 倍(调整后的优势比(OR)1.85,95%可信区间 1.20 至 2.93)。与白人女性相比,非裔美国人和亚裔女性接种疫苗的可能性分别较低。风险认知与疫苗接种率没有显著相关,但大多数受访者未能准确识别他们感染和传播 HPV 的高风险。

结论

这些发现表明,针对这一亚群的 HPV 预防疫苗的使用,教育活动中可能需要强调 HPV 风险的知识缺陷和误解。

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