一名乙型血友病患者在接受凝血酶原复合物浓缩剂治疗期间发生弥散性血管内凝血和心肌梗死。
Disseminated intravascular coagulation and myocardial infarction in a haemophilia B patient during therapy with prothrombin complex concentrates.
作者信息
Chistolini A, Mazzucconi M G, Tirindelli M C, La Verde G, Ferrari A, Mandelli F
机构信息
Department of Human Biopathology, University La Sapienza, Rome, Italy.
出版信息
Acta Haematol. 1990;83(3):163-5. doi: 10.1159/000205197.
PMID:2109459
Abstract
A case of disseminated intravascular coagulation (DIC) and fatal myocardial infarction in a haemophilia B patient is described. DIC occurred after 4 days of therapy with unactivated prothrombin complex concentrates during the post-operative period. Therapy with fresh frozen plasma, heparin and antithrombin III concentrates was started without efficacy; after autopsy myocardial infarction was evident.
摘要
本文描述了1例乙型血友病患者发生弥散性血管内凝血（DIC）并导致致命性心肌梗死的病例。该患者在术后接受未活化凝血酶原复合物浓缩剂治疗4天后发生DIC。随后开始使用新鲜冰冻血浆、肝素和抗凝血酶III浓缩剂进行治疗，但均无效；尸检显示存在明显的心肌梗死。
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