Leuven Institute for Fertility and Embryology, Leuven, Belgium.
Am J Obstet Gynecol. 2011 Mar;204(3):193-201. doi: 10.1016/j.ajog.2010.08.009. Epub 2010 Nov 20.
Defective deep placentation has been associated with a spectrum of complications of pregnancy including preeclampsia, intrauterine growth restriction, preterm labor, preterm premature rupture of membranes, late spontaneous abortion, and abruptio placentae. The disease of the placental vascular bed that underpins these complications is commonly investigated with targeted biopsies. In this review, we critically evaluate the biopsy technique to summarize the salient types of defective deep placentation, and propose criteria for the classification of defective deep placentation into 3 types based on the degree of restriction of remodeling and the presence of obstructive lesions in the myometrial segment of the spiral arteries.
胎盘深部植入缺陷与一系列妊娠并发症相关，包括子痫前期、宫内生长受限、早产、胎膜早破早产、晚期自然流产和胎盘早剥。这些并发症所对应的胎盘血管床疾病通常通过靶向活检进行研究。在这篇综述中，我们批判性地评估了活检技术，总结了胎盘深部植入缺陷的主要类型，并基于螺旋动脉肌壁段重塑受限的程度和阻塞性病变的存在，提出了将胎盘深部植入缺陷分为 3 型的分类标准。
