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肉瘤样反应模仿肺癌诱导化疗后疾病的进展。

Sarcoid-like reaction mimics progression of disease after induction chemotherapy for lung cancer.

机构信息

Department of General Thoracic Surgery, Dokkyo Medical University, Tochigi, Japan.

出版信息

Ann Thorac Surg. 2010 Dec;90(6):2031-3. doi: 10.1016/j.athoracsur.2010.06.014.

DOI:10.1016/j.athoracsur.2010.06.014
PMID:21095358
Abstract

The use of 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET) for staging nonsmall cell lung cancer is widely recognized, whereas the value of fluorodeoxyglucose-positron emission tomography imaging in the evaluation of response to induction chemotherapy is still controversial. We describe a case of a 57-year-old man who had a sarcoid-like reaction develop during induction chemotherapy for a pathologically proven N2 lung cancer. Re-evaluation of the nodal status using fluorodeoxyglucose-positron emission tomography showed false-positive accumulation in the mediastinal and hilar lymph nodes, which led us to suspect lung cancer progression after induction chemotherapy.

摘要

正电子发射断层扫描(FDG-PET)在非小细胞肺癌分期中的应用已被广泛认可,然而氟脱氧葡萄糖正电子发射断层扫描成像在评估诱导化疗反应中的价值仍存在争议。我们描述了一例 57 岁男性患者,在病理证实为 N2 肺癌的诱导化疗期间发生类肉瘤样反应。使用氟脱氧葡萄糖正电子发射断层扫描重新评估淋巴结状态时,纵隔和肺门淋巴结出现假阳性堆积,这使我们怀疑诱导化疗后肺癌进展。

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