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紫药水及类似产品治疗皮肤脓皮病的疗效。

Effectiveness of gentian violet and similar products commonly used to treat pyodermas.

机构信息

Department of Dermatology, Emory University School of Medicine, Atlanta, GA 30322, USA.

出版信息

Dermatol Clin. 2011 Jan;29(1):69-73. doi: 10.1016/j.det.2010.08.009.

Abstract

The term pyoderma encompasses a variety of distinct entities including impetigo (bullous and nonbullous), erysipelas, cellulitis, folliculitis, and staphylococcal scalded skin syndrome. Treatment of pyodermas centers around wound care and appropriate antibiotic selection. Triphenylmethane dyes, such as gentian violet, represent a unique group of compounds that act as antiseptics and have shown clinical efficacy as antibiotics in a variety of pyodermas, including those secondary to methicillin-resistant Staphylococcus aureus. Given their low cost, ease of application, and favorable side effect profile, triphenylmethanes must be considered legitimate treatment options for pyodermas, particularly in the face of continued and emerging bacterial resistance.

摘要

脓疱病包括多种不同的实体,包括脓疱疮(大疱性和非大疱性)、丹毒、蜂窝织炎、毛囊炎和葡萄球菌性烫伤样皮肤综合征。脓疱病的治疗主要集中在伤口护理和适当的抗生素选择上。三苯甲烷染料,如龙胆紫,代表了一组独特的化合物,它们具有防腐剂的作用,并已在多种脓疱病中显示出临床疗效,包括耐甲氧西林金黄色葡萄球菌引起的脓疱病。鉴于其成本低、使用方便且副作用小,三苯甲烷类药物必须被视为脓疱病的合法治疗选择,特别是在面对持续和新出现的细菌耐药性时。

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