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Analysis of trial-by-trial variability in stimulus-evoked neural activity.

作者信息

Raman Baranidharan, Stopfer Mark

机构信息

Department of Biomedical Engineering, Washington University, St. Louis, MO 63136, USA.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:4320-2. doi: 10.1109/IEMBS.2010.5626198.

DOI:10.1109/IEMBS.2010.5626198
PMID:21095757
Abstract

Using standard dimensionality reduction analysis we examined the stimulus-evoked neural activity over time and their variability across trials. Consistent with earlier results, we found that odor pulses evoked spatio-temporal responses distributed throughout an ensemble of simultaneous recorded neurons. Responses clustered based on odor identity despite the presence of a relatively small amount of trial-by-trial variability. We found that this scatter across trials can be reduced using a simple linear projection of the data.

摘要

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