一种用于具有几乎任意电流波形的通用神经刺激器的架构。

An architecture for a universal neural stimulator with almost arbitrary current waveform.

作者信息

Noorsal Emilia, Ortmanns Maurits

机构信息

Institute of Microelectronics, University of Ulm, 89081 Ulm, Germany.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:2931-4. doi: 10.1109/IEMBS.2010.5626293.

Abstract

This paper describes the architecture and protocol of a digital stimulator which is intended to realize a highly flexible stimulation waveform pattern. The flexibility is provided by programmable stimulation profiles such as pulse duration, frequency, polarity, amplitude level, arbitrary wave shape, train of pulses and different types of wave patterns among stimulation sites. The programmable stimulation data is therefore divided into two parts, global and local stimulation data. The global data which defines the timing of pulse duration and wave shaping, are sent sequentially to all stimulation sites using 5-bit control commands. Local stimulation data defines the initial amplitude setting and is stored at each active stimulation cell. At each stimulation site, the amplitude level can be changed during the stimulation process and consequently it generates an arbitrary wave shape. Without the need of a large memory size, the proposed simple design architecture generates not only arbitrary stimulation waveforms, but also trains of pulses as well as different types of stimulation patterns among stimulation sites are enabled.

摘要

本文描述了一种数字刺激器的架构和协议,该刺激器旨在实现高度灵活的刺激波形模式。这种灵活性由可编程刺激参数提供,如脉冲持续时间、频率、极性、幅度水平、任意波形、脉冲序列以及刺激部位之间不同类型的波形模式。因此,可编程刺激数据分为两部分,全局和局部刺激数据。定义脉冲持续时间和波形整形定时的全局数据,使用5位控制命令顺序发送到所有刺激部位。局部刺激数据定义初始幅度设置,并存储在每个激活的刺激单元中。在每个刺激部位,幅度水平可以在刺激过程中改变,从而产生任意波形。所提出的简单设计架构无需大内存,不仅能生成任意刺激波形,还能生成脉冲序列以及实现刺激部位之间不同类型的刺激模式。

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