Gallassi R, Morreale A, Lorusso S, Procaccianti G, Lugaresi E, Baruzzi A
Institute of Neurology, University of Bologna, Italy.
Epilepsy Res. 1990 Mar;5(2):160-4. doi: 10.1016/0920-1211(90)90033-r.
The effects of valproate on cognition are usually considered to be minimal, but few formal neuropsychological studies are available. We studied the psychomotor performances of 20 seizure-free epileptics during fixed valproate monotherapy and after its withdrawal. Our findings suggest some adverse effects of valproate which appear to be completely reversible after withdrawal.