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The peptidoglycan of Mycobacterium abscessus is predominantly cross-linked by L,D-transpeptidases.
J Bacteriol. 2011 Feb;193(3):778-82. doi: 10.1128/JB.00606-10. Epub 2010 Nov 19.
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In vitro cross-linking of Mycobacterium tuberculosis peptidoglycan by L,D-transpeptidases and inactivation of these enzymes by carbapenems.
Antimicrob Agents Chemother. 2013 Dec;57(12):5940-5. doi: 10.1128/AAC.01663-13. Epub 2013 Sep 16.
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Identification of the L,D-transpeptidases for peptidoglycan cross-linking in Escherichia coli.
J Bacteriol. 2008 Jul;190(13):4782-5. doi: 10.1128/JB.00025-08. Epub 2008 May 2.
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LdtC Is a Key l,d-Transpeptidase for Peptidoglycan Assembly in Mycobacterium smegmatis.
J Bacteriol. 2023 Jan 26;205(1):e0042422. doi: 10.1128/jb.00424-22. Epub 2022 Dec 21.
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Identification of a Functionally Unique Family of Penicillin-Binding Proteins.
J Am Chem Soc. 2017 Dec 13;139(49):17727-17730. doi: 10.1021/jacs.7b10170. Epub 2017 Nov 30.
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Covalent attachment of proteins to peptidoglycan.
FEMS Microbiol Rev. 2008 Mar;32(2):307-20. doi: 10.1111/j.1574-6976.2008.00102.x. Epub 2008 Feb 11.
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Cleavage of Braun's lipoprotein Lpp from the bacterial peptidoglycan by a paralog of l,d-transpeptidases, LdtF.
Proc Natl Acad Sci U S A. 2021 May 11;118(19). doi: 10.1073/pnas.2101989118.
9
Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins.
Antimicrob Agents Chemother. 2017 Sep 22;61(10). doi: 10.1128/AAC.00866-17. Print 2017 Oct.
10
Peptidoglycan Cross-Linking Activity of l,d-Transpeptidases from Clostridium difficile and Inactivation of These Enzymes by β-Lactams.
Antimicrob Agents Chemother. 2017 Dec 21;62(1). doi: 10.1128/AAC.01607-17. Print 2018 Jan.

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Durlobactam in combination with β-lactams to combat .
Antimicrob Agents Chemother. 2025 Feb 13;69(2):e0117424. doi: 10.1128/aac.01174-24. Epub 2024 Dec 23.
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The use of dual β-lactams to restore susceptibility of complex.
JAC Antimicrob Resist. 2024 Sep 13;6(5):dlae142. doi: 10.1093/jacamr/dlae142. eCollection 2024 Oct.
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Control of bacterial cell wall autolysins by peptidoglycan crosslinking mode.
Nat Commun. 2024 Sep 11;15(1):7937. doi: 10.1038/s41467-024-52325-2.
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Evolution toward extremely high imipenem resistance in outbreak strains.
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Evolution towards extremely high β-lactam resistance in outbreak strains.
bioRxiv. 2024 May 9:2024.05.08.593223. doi: 10.1101/2024.05.08.593223.
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New therapeutic strategies for pulmonary diseases - untapping the mycolic acid pathway.
Expert Rev Anti Infect Ther. 2023 Jul-Dec;21(8):813-829. doi: 10.1080/14787210.2023.2224563. Epub 2023 Jun 23.
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Characterization of Pseudomonas aeruginosa l,d-Transpeptidases and Evaluation of Their Role in Peptidoglycan Adaptation to Biofilm Growth.
Microbiol Spectr. 2023 Aug 17;11(4):e0521722. doi: 10.1128/spectrum.05217-22. Epub 2023 May 31.
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LdtC Is a Key l,d-Transpeptidase for Peptidoglycan Assembly in Mycobacterium smegmatis.
J Bacteriol. 2023 Jan 26;205(1):e0042422. doi: 10.1128/jb.00424-22. Epub 2022 Dec 21.

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Construction of Mycobacterium abscessus defined glycopeptidolipid mutants: comparison of genetic tools.
Appl Environ Microbiol. 2009 Mar;75(5):1331-8. doi: 10.1128/AEM.01914-08. Epub 2008 Dec 29.
7
Evolution of peptidoglycan biosynthesis under the selective pressure of antibiotics in Gram-positive bacteria.
FEMS Microbiol Rev. 2008 Mar;32(2):386-408. doi: 10.1111/j.1574-6976.2007.00097.x. Epub 2008 Feb 11.
8
The penicillin-binding proteins: structure and role in peptidoglycan biosynthesis.
FEMS Microbiol Rev. 2008 Mar;32(2):234-58. doi: 10.1111/j.1574-6976.2008.00105.x. Epub 2008 Feb 11.
9
Structural variation in the glycan strands of bacterial peptidoglycan.
FEMS Microbiol Rev. 2008 Mar;32(2):287-306. doi: 10.1111/j.1574-6976.2007.00088.x. Epub 2007 Dec 5.
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Unique structural features of the peptidoglycan of Mycobacterium leprae.
J Bacteriol. 2008 Jan;190(2):655-61. doi: 10.1128/JB.00982-07. Epub 2007 Nov 16.

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