Glatstein Miguel, Carbell Gary, Boddu Sirisha Kusuma, Bernardini Annalucia, Scolnik Dennis
University of Toronto, and Division of Pediatric Emergency Medicine, The Hospital for Sick Children, 555 University Ave., Toronto, Ontario, Canada.
Clin Pediatr (Phila). 2011 Mar;50(3):192-5. doi: 10.1177/0009922810384846. Epub 2010 Nov 22.
The authors reviewed the clinical and laboratory data from cases of hypertrophic pyloric stenosis (HPS) diagnosed at their institution from 2006 to 2008. They assessed and compared presentation of patients with HPS over time at their institution. A total of 118 patients were included in this study. An "olive" was palpated in only 13.6% of cases. This is in contrast to older studies, where more than 50% of the patients were reported to have a palpable "olive" depending on when the study was conducted. In patients from this institution, hypochloremia was present in 23% and alkalosis in 14.4%, which are less frequent than the incidence of these abnormalities in older studies. There was a change in the additional "classical" symptoms, represented by the lower percentage of infants in whom an "olive" was palpated and the lower numbers of patients with severe electrolyte imbalances. The reason for this change appears to be the frequent use of ultrasound.
作者回顾了2006年至2008年在其机构诊断为肥厚性幽门狭窄(HPS)的病例的临床和实验室数据。他们评估并比较了该机构不同时间点HPS患者的临床表现。本研究共纳入118例患者。仅13.6%的病例可触及“橄榄样肿物”。这与以往的研究不同,以往研究中根据研究开展的时间不同,报告有超过50%的患者可触及“橄榄样肿物”。在该机构的患者中,23%存在低氯血症,14.4%存在碱中毒,这些情况比以往研究中这些异常情况的发生率要低。以可触及“橄榄样肿物”的婴儿比例降低以及严重电解质失衡患者数量减少为代表的其他“经典”症状出现了变化。这种变化的原因似乎是超声的频繁使用。