Department of Medical Zoology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Jpn J Infect Dis. 2010 Nov;63(6):447-8.
Human ascariasis is caused by infection with the common roundworm Ascaris lumbricoides, although the pig roundworm Ascaris suum has also been reported to infect humans and develop into the adult stage. To elucidate whether pig-derived Ascaris infects humans in Japan, 9 Ascaris isolates obtained from Japanese patients and a further 9 Ascaris isolates of pig origin were analyzed to determine their internal transcribed spacer-1 sequences. Six of the 9 clinical isolates showed the Ascaris genotype which predominantly infects humans in endemic countries, while the other 3 clinical isolates and 9 pig-derived isolates showed the genotype predominant in pigs worldwide. These results suggest that at least some cases of human ascariasis in Japan are a result of infection with pig-derived Ascaris.
人蛔虫病是由感染常见的蛔虫引起的，尽管猪蛔虫也曾有报道感染人类并发育为成虫。为了阐明在日本猪蛔虫是否感染人类，对从日本患者中获得的 9 株蛔虫分离株和另外 9 株猪源蛔虫分离株进行了分析，以确定它们的内转录间隔区 1 序列。9 株临床分离株中的 6 株显示出在流行地区主要感染人类的蛔虫基因型，而其他 3 株临床分离株和 9 株猪源分离株显示出在世界范围内猪中流行的基因型。这些结果表明，在日本至少有一些人类蛔虫病是由猪源蛔虫感染引起的。
