Manusharova R A, Bezverkhaia T P
Vrach Delo. 1990 Jan(1):37-9.
The authors examined the level of gonadotropin (lutropin, follitropin) and sex steroids (estradiol, progesteron, testosterone) before and after administration of thyroliberin in 10 healthy women and 15 females suffering of Itsenko-Cushing disease. It was established that both the healthy and patients with Itsenko-Cushing disease did not reveal any significant changes in the level of lutropin, follitropin, estradiol, progesteron, testosteron after administration of thyroliberin within 2 hours of the examination. Data indicate absence of paradoxic response of gonadotropins and cells secreting sex steroids in Itsenko-Cushing disease.
作者检测了10名健康女性和15名患有库欣病的女性在注射促甲状腺素前后促性腺激素（促黄体生成素、促卵泡生成素）和性类固醇（雌二醇、孕酮、睾酮）的水平。结果表明，在检查的2小时内，健康女性和库欣病患者在注射促甲状腺素后，促黄体生成素、促卵泡生成素、雌二醇、孕酮、睾酮水平均未出现任何显著变化。数据表明库欣病患者不存在促性腺激素和分泌性类固醇细胞的反常反应。
