Vanage G R, Gopalkrishnan K, Sheth A R
Institute for Research in Reproduction (ICMR), Bombay, India.
Mol Reprod Dev. 1990 Mar;25(3):227-36. doi: 10.1002/mrd.1080250304.
In vitro incubation of rat epididymal sperm with antiserum to human seminal plasma inhibin (As hSPI) caused agglutination of the sperm. In vivo administration of As hSPI to adult male rats resulted in a significant decrease in testicular as well as epididymal sperm counts. Furthermore, the majority (almost 90%) of the epididymal sperm were agglutinated. When these animals were mated with normal cycling females, significant reduction in fertility was observed.
将大鼠附睾精子与抗人类精浆抑制素抗血清（As hSPI）进行体外孵育会导致精子凝集。对成年雄性大鼠进行As hSPI体内给药后，睾丸和附睾中的精子数量显著减少。此外，附睾中大部分（近90%）的精子发生凝集。当这些动物与正常发情周期的雌性动物交配时，观察到生育力显著降低。
