Tanbo T, Dale P O, Kjekshus E, Haug E, Abyholm T
National Hospital, University of Oslo, Norway.
Fertil Steril. 1990 May;53(5):798-803. doi: 10.1016/s0015-0282(16)53512-2.
Stimulation with human menopausal gonadotropin (hMG) or follicle-stimulating hormone (FSH) was compared in 34 patients with polycystic ovarian syndrome after pituitary gonadotrope suppression with buserelin acetate. No differences were seen in the hormone parameters observed. Also, the duration of the stimulation period and the dose of gonadotropin used were the same. In both groups a multifollicular response was seen. Oocyte retrieval and in vitro fertilization resulted in identical ratios of mature to total oocytes and cleavage rates. Nine pregnancies occurred, four in the hMG group and five in the FSH group. Of the nine pregnancies, two were the result of transfer of frozen-thawed embryos in estradiol and progesterone substituted cycles.
在34例多囊卵巢综合征患者中，使用醋酸布舍瑞林抑制垂体促性腺激素后，比较了人绝经期促性腺激素（hMG）和促卵泡激素（FSH）刺激的效果。观察到的激素参数没有差异。此外，刺激期的持续时间和使用的促性腺激素剂量相同。两组均出现多卵泡反应。取卵和体外受精产生的成熟卵母细胞与总卵母细胞的比率以及卵裂率相同。共发生9例妊娠，hMG组4例，FSH组5例。在这9例妊娠中，有2例是在雌激素和孕激素替代周期中移植冻融胚胎的结果。
