Thomson G T, Johnston J L, Baragar F D, Toole J W
Department of Medicine, University of Manitoba, Winnipeg, Canada.
J Rheumatol. 1990 Mar;17(3):395-8.
We describe a patient with psoriatic arthritis and a myopathy. The myopathy did not follow the time course of topical steroid treatment, nor did the patient display any features of hypercorticolism or local steroid excess. No evidence was found to support the diagnosis of polymyositis. Psoriatic myopathy is an uncommonly described condition. Steroid induced myopathy shares some nonspecific features with psoriatic myopathy, but can be differentiated by the clinical response to cessation of steroid therapy. Myalgia and 24 h urine creatine elevation are 2 features not previously described in association with psoriatic myopathy. The latter appears to correlate with muscle weakness and may be useful in following the course of this disease.
我们描述了一名患有银屑病关节炎和肌病的患者。该肌病并不随局部类固醇治疗的时间进程发展,患者也未表现出任何皮质醇增多症或局部类固醇过量的特征。未发现支持多发性肌炎诊断的证据。银屑病性肌病是一种较少被描述的病症。类固醇诱导的肌病与银屑病性肌病有一些非特异性特征,但可通过停止类固醇治疗后的临床反应进行区分。肌痛和24小时尿肌酸升高是此前未与银屑病性肌病相关联描述过的两个特征。后者似乎与肌肉无力相关,可能有助于追踪该疾病的病程。