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本文引用的文献
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Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer.
Nat Commun. 2010 Apr 12;1:3. doi: 10.1038/ncomms1001.
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SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism.
J Biol Chem. 2010 Oct 29;285(44):33959-70. doi: 10.1074/jbc.M110.122978. Epub 2010 Sep 3.
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Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis.
Cell Metab. 2010 Sep 8;12(3):224-36. doi: 10.1016/j.cmet.2010.06.009.
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SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus.
J Neurosci. 2010 Jul 28;30(30):10220-32. doi: 10.1523/JNEUROSCI.1385-10.2010.
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SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.
Cell. 2010 Jul 23;142(2):320-32. doi: 10.1016/j.cell.2010.06.020.
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Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress.
Mol Cell Biol. 2010 Oct;30(19):4712-21. doi: 10.1128/MCB.00657-10. Epub 2010 Jul 20.
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SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity.
Cell Metab. 2010 Jul 7;12(1):78-87. doi: 10.1016/j.cmet.2010.05.010.
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SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
Aging (Albany NY). 2010 Jun;2(6):353-60. doi: 10.18632/aging.100162.
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Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.
Genes Dev. 2010 Jul 1;24(13):1403-17. doi: 10.1101/gad.1901210.
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Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation.
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