Gold Michael H, Pope Amy
J Clin Aesthet Dermatol. 2008 May;1(1):30-3.
Fractional resurfacing has become a very popular laser modality in recent years, and photodynamic therapy (PDT) has become a mainstay of many practices treating a wide array of clinical entities. In this case report, we describe a recalcitrant verrucous lesion on the foot that is unresponsive to cryotherapy, pulsed dye laser, and pulsed dye laser with PDT. The lesion did, however, respond very well to the use of a fractional laser to enhance the penetration of the PDT photosensitizer and then responded to pulsed dye laser with PDT. Fractional resurfacing prior to PDT may be a novel dermatologic treatment approach, making PDT an even better treatment option in the future.
近年来,分次嫩肤已成为一种非常流行的激光治疗方式,光动力疗法(PDT)已成为许多医疗机构治疗多种临床病症的主要手段。在本病例报告中,我们描述了一例足部顽固性疣状病变,该病变对冷冻疗法、脉冲染料激光以及联合光动力疗法的脉冲染料激光均无反应。然而,该病变对使用分次激光增强光动力疗法光敏剂的渗透反应良好,随后对联合光动力疗法的脉冲染料激光有反应。在光动力疗法之前进行分次嫩肤可能是一种新的皮肤病治疗方法,有望使光动力疗法在未来成为更好的治疗选择。