Service d'Ophtalmologie, Hopital Saint Roch, 5 rue Pierre Dévoluy, 06000, Nice Cedex 1, France.
Graefes Arch Clin Exp Ophthalmol. 2011 Jun;249(6):827-31. doi: 10.1007/s00417-010-1560-1. Epub 2010 Nov 20.
Acute macular neuroretinopathy is a rare disease which occurs in young women and causes sudden paracentral scotoma and typical reddish-brown macular lesions.
We report two cases of young women suffering from acute macular neuroretinopathy which we observed with spectral-domain Spectralis HRA-OCT and multifocal ERG at 3 and 7 months.
Imaging revealed an early hyper-reflectivity of the photoreceptor layer, which changed into hyporeflectivity in the first week and remained the same in the following months, whereas visual field improved.
Our findings show involvement primarly of the outer retina, and confirm OCT and mf ERG as important tools for diagnosis and follow-up of pathologic changes in AMNR, as other diagnostic tests often remain normal.
急性黄斑神经视网膜病变是一种罕见疾病,发生于年轻女性,可导致突发性旁中心暗点和典型的棕红色黄斑病变。
我们报告了两例年轻女性急性黄斑神经视网膜病变的病例,我们在发病后 3 个月和 7 个月分别使用频域光学相干断层扫描(Spectralis HRA-OCT)和多焦视网膜电图(mf ERG)进行了观察。
影像学显示早期光感受器层的高反射性,在第一周变为低反射性,并在随后的几个月保持不变,而视野改善。
我们的发现表明主要累及外视网膜,证实 OCT 和 mf ERG 是诊断和随访 AMNR 病理改变的重要工具,因为其他诊断测试通常正常。