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挪威使用通用降压药物的患者:一项关于他们自身体验的定性研究。

Norwegian patients on generic antihypertensive drugs: a qualitative study of their own experiences.

机构信息

Department of Social Pharmacy, School of Pharmacy, University of Oslo, Oslo, Norway.

出版信息

Eur J Clin Pharmacol. 2011 Jan;67(1):33-8. doi: 10.1007/s00228-010-0935-x. Epub 2010 Nov 23.

Abstract

OBJECTIVES

The aim of this study was to investigate experiences with and attitudes toward generic substitution in patients on antihypertensive medication.

MATERIALS AND METHODS

Study participants were 22 patients from pharmacies in Oslo who had taken brand antihypertensive products as well as substituted generic products. Five focus- group discussions were held.

RESULTS

Only a few participants claimed to take their medications as prescribed. Most reported low drug adherence before and after generic substitution. Fourteen said that their blood pressure was not under control. Most patients did not know what it meant to get a generic product. They normally accepted what the pharmacy offered, even if they thought the generics were of a lower quality than the brand products. Five participants experienced new side effects. Differences in name, color, form, or taste caused confusion. The patients had been told in the pharmacy that the effect of a generic product was as good as that of the brand product but were still confused, as in most cases the doctor said nothing to them about the substitution.

CONCLUSION

Generic substitution works well in Norway as an economic health strategy, but drug adherence remains suboptimal under those circumstances. Patients are insecure with respect to the difference between the old and the new product when it comes to the drug's physical attributes and perceived quality. Patients would feel safer if the doctor had a more active role in informing them about the system.

摘要

目的

本研究旨在调查服用降压药物的患者对仿制药替代的体验和态度。

材料和方法

研究参与者是来自奥斯陆药房的 22 名患者,他们曾服用过品牌降压产品和替代的仿制药。进行了 5 次焦点小组讨论。

结果

只有少数参与者声称按规定服用药物。大多数人报告在仿制药替代前后的药物依从性较低。14 人表示他们的血压未得到控制。大多数患者不知道获得仿制药意味着什么。他们通常接受药房提供的药物,即使他们认为仿制药的质量比品牌产品低。5 名参与者出现了新的副作用。名称、颜色、形式或味道的差异引起了混淆。患者在药房被告知仿制药的效果与品牌药一样好,但仍感到困惑,因为在大多数情况下,医生没有向他们提及替代药物。

结论

仿制药替代在挪威作为一种经济的健康策略效果良好,但在这种情况下,药物依从性仍然不理想。当涉及药物的物理属性和感知质量时,患者对新旧产品之间的差异感到不安。如果医生在告知患者有关该系统方面发挥更积极的作用,患者会感到更安全。

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