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马来西亚患者对非专利药品的看法。

Patients' beliefs about generic medicines in Malaysia.

作者信息

Wong Zhi Y, Hassali Mohamed A, Alrasheedy Alian A, Saleem Fahad, Yahaya Abdul H, Aljadhey Hisham

机构信息

Pharmacy Department, Hospital Teluk Intan. Perak ( Malaysia ).

Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia . Penang ( Malaysia ).

出版信息

Pharm Pract (Granada). 2014 Oct;12(4):474. doi: 10.4321/s1886-36552014000400006. Epub 2014 Mar 15.

Abstract

BACKGROUND

Acceptance of generic medicines by patients is an essential factor given that they are the end users of these medicines. In fact, adequate knowledge and positive perceptions are prerequisite to patients' acceptance and use of generic medicines.

OBJECTIVE

To assess the current belief and views of patients about generic medicines in Malaysia.

METHOD

This was a self-administered questionnaire-based study. The study was conducted with patients visiting outpatient pharmacy department at a tertiary care hospital in Malaysia. The Malaysian version of Generic Medicines Scale (GMS) was used. The GMS consists of two subscales: efficacy and similarity of generic medicines to original brand medicines. The efficacy subscale consists of 10 items while the similarity subscale consists of 6 items. The responses to the items were framed as a five-point Likert scale (1=strongly disagree to 5=strongly agree).

RESULTS

A total of 202 out of 300 patients participated in the study, giving a response rate of 67.3%. In this study, only 49% of them (n=99) knew the term 'generic medicine'. Moreover, only 53.5% of the respondents (n=108) believed that the efficacy of generic medicines was the same as original brand medicines. In terms of quality, only 44% of the respondents (n=89) disagreed that generic medicines were of a lower quality. About one third (n=65, 32.2%) believed that generic medicines were cheaper because they were less efficacious. In terms of side effects, 44.5% of the respondents (n=90) believed that generic medicines had the same side effect profile as original brand medicines.

CONCLUSIONS

The study finding showed that almost half of the respondents had negative belief in generic medicines. Similarly, many patients were not aware of the similarities and differences between generic and original brand medicines. Therefore, there is a need to provide patients with adequate information about generic medicines.

摘要

背景

鉴于患者是通用药物的最终使用者,患者对通用药物的接受程度是一个关键因素。事实上,充分的了解和积极的认知是患者接受和使用通用药物的前提条件。

目的

评估马来西亚患者对通用药物的当前认知和看法。

方法

这是一项基于自填问卷的研究。研究对象为前往马来西亚一家三级护理医院门诊药房就诊的患者。使用了马来西亚版的通用药物量表(GMS)。GMS由两个子量表组成:通用药物与原研品牌药物的疗效及相似性。疗效子量表包含10个项目,相似性子量表包含6个项目。对这些项目的回答采用五点李克特量表(1 = 强烈不同意至5 = 强烈同意)。

结果

300名患者中共有202名参与了研究,回复率为67.3%。在本研究中,只有49%(n = 99)的患者知道“通用药物”这个术语。此外,只有53.5%(n = 108)的受访者认为通用药物的疗效与原研品牌药物相同。在质量方面,只有44%(n = 89)的受访者不同意通用药物质量较低的观点。约三分之一(n = 65,32.2%)的受访者认为通用药物更便宜是因为其疗效较差。在副作用方面,44.5%(n = 90)的受访者认为通用药物与原研品牌药物具有相同的副作用特征。

结论

研究结果表明,近一半的受访者对通用药物持有负面看法。同样,许多患者并不了解通用药物与原研品牌药物之间的异同。因此,有必要向患者提供关于通用药物的充分信息。

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