School of Medicine, University of Varmia, and Masuria, Olsztyn, Poland.
Endokrynol Pol. 2010 Nov-Dec;61(6):671-82.
The aim of this study was an investigation into the individual and socio-economic risk factors of the incidence of thyroid carcinoma.
Our study was into risk factors affecting the incidence of thyroid carcinoma conducted in patients included in a register of thyroid carcinoma. For that purpose, a questionnaire was prepared which covered personal information, medical history and socio-economic factors. A statistical analysis was conducted.
The register comprised 297 patients (89% female) with thyroid carcinoma and 589 healthy subjects. Age group distribution was similar for both groups. The largest group was aged 50-54. The number of children born to women with carcinoma and women in the control group did not differ significantly. 10% of the women with carcinoma had used contraception. Patients were most frequently born in Olsztyn province, an area of relative iodine deficiency. 9.72% had suffered from thyroid disease in childhood. 32.41% had a family history of thyroid disease. Mothers of patients most frequently also came from regions of similar iodine level. The fathers most frequently came from Warsaw province (17.08%). The origin of the remainder was the same as of the mothers. 36% of patients had elementary, 14% vocational, 38% secondary and 13% higher education. Logistic regression showed that the risk of carcinoma increased 0.98 times in each person younger by a year. Individuals with body mass lower had 0.98 times greater risk of the disease by each kilogram.
The risk factors for the incidence of thyroid carcinoma: female sex, age at onset, low body mass.
本研究旨在调查甲状腺癌发病的个体和社会经济风险因素。
我们的研究是在甲状腺癌登记处纳入的患者中进行的,旨在研究影响甲状腺癌发病的风险因素。为此,我们准备了一份问卷,涵盖了个人信息、病史和社会经济因素。进行了统计分析。
该登记册包括 297 名(89%为女性)甲状腺癌患者和 589 名健康对照者。两组的年龄分布相似。最大的年龄组为 50-54 岁。患有癌症的女性和对照组女性所生的孩子数量没有显著差异。10%的女性使用过避孕药。患者最常出生在相对缺碘的奥尔什丁省。9.72%的人在儿童时期患有甲状腺疾病。32.41%的人有甲状腺疾病家族史。患者的母亲最常来自类似碘水平的地区。父亲最常来自华沙省(17.08%)。其余人的原籍与母亲相同。36%的患者接受过小学教育,14%接受过职业教育,38%接受过中学教育,13%接受过高等教育。逻辑回归显示,每年年轻一岁,患癌风险增加 0.98 倍。体重每减少一公斤,患病风险增加 0.98 倍。
甲状腺癌发病的风险因素:女性、发病年龄、低体重指数。