Koval'zon V M, Tsibul'skiĭ V L
Fiziol Zh SSSR Im I M Sechenova. 1978 Aug;64(8):1082-8.
Rats were repeatedly arused from REM sleep by the stimulation via implanted midbrain reticular electrodes. The 4-day seprivation reduced REM sleep by 50% whereas the slow-wave sleep was only reduced by 10%. There was no evidence of a disruption in the animal behaviour during the deprivation and no changes of emotional responsiveness in the "open-field" at the end of the deprivation. REM deprivation produced a slight but statistically significant (P = 0.025) adrenal weightlos. Thymus weight was unchanged and no stomach ulcers developed. Therefore the REM deprivation as such did not appear to produce stress in rats.
通过植入中脑网状电极进行刺激,反复唤醒处于快速眼动睡眠期的大鼠。4天的剥夺使快速眼动睡眠减少了50%,而慢波睡眠仅减少了10%。在剥夺期间没有动物行为紊乱的迹象,剥夺结束时在“旷场”实验中动物的情绪反应性也没有变化。快速眼动睡眠剥夺导致肾上腺重量略有减轻,但具有统计学意义(P = 0.025)。胸腺重量未改变,也未出现胃溃疡。因此,单纯的快速眼动睡眠剥夺似乎不会在大鼠中产生应激反应。