Sydney Medical School, Sydney Adventist Hospital, University of Sydney, Sydney, Australia.
BJU Int. 2011 Sep;108(6):860-3. doi: 10.1111/j.1464-410X.2010.09855.x. Epub 2010 Nov 24.
OBJECTIVE • To evaluate experience with high power LBO laser for large prostates
• Prospective database of 288 men treated with PVP from November 2006-2009 • 33 men identified to have transrectal ultrasound measured prostate size >120 cc • All but 9 men not in urinary retention or on anticoagulant medications • Average ASA Score 2.25 (range 1-4) with 11 having an ASA Score of 3 or more
• Mean operating time and laser time 109 and 86 minutes respectively • IPSS, QoL and Qmax changes from baseline to 3 months for those not in retention were 24 to 8.6, 5.0 to 1.8 and 7.5 mL/s to 19.6 mL/s respectively • Post void residual in these men fell from a mean of 235 mL to 88 mL • Average fall in PSA was 38% for 22 men with paired PSA data • Post operative urinary retention in 4 men resolved. 2 late onset clot urinary retention
• Early results demonstrate PVP to be safe and efficacious on early follow up in a high risk group of patients with significantly enlarged prostates, anticoagulation and urinary retention.
目的•评估大功率 LBO 激光治疗大前列腺的经验。
•2006 年 11 月至 2009 年 PVP 治疗的 288 名男性的前瞻性数据库•33 名经直肠超声测量前列腺体积> 120 cc 的男性确定•除 9 名男性外,均无尿潴留或抗凝药物治疗•平均 ASA 评分为 2.25(范围 1-4),其中 11 名 ASA 评分为 3 或更高。
•平均手术时间和激光时间分别为 109 分钟和 86 分钟•IPSS、QoL 和 Qmax 从基线到 3 个月的变化对于未保留的患者分别为 24 至 8.6、5.0 至 1.8 和 7.5 mL/s 至 19.6 mL/s•这些男性的剩余尿量从平均 235 毫升降至 88 毫升•22 名具有配对 PSA 数据的男性平均 PSA 下降 38%•4 名男性术后尿潴留得到解决。2 例迟发性血栓尿潴留。
•早期结果表明,在高风险组、抗凝和尿潴留的高危患者中,PVP 在早期随访中安全有效。