结直肠癌中的Ascl2与11p15.5扩增 - Suppr

Suppr

超能文献

Ascl2 and 11p15.5 amplification in colorectal cancer.

作者信息

Jubb Adrian M, Hoeflich Klaus P, Haverty Peter M, Wang Jennifer, Koeppen Hartmut

出版信息

Gut. 2011 Nov;60(11):1606-7; author reply 1607. doi: 10.1136/gut.2010.231746. Epub 2010 Nov 23.

DOI:10.1136/gut.2010.231746

PMID:21106550

Abstract

摘要

相似文献

Ascl2 and 11p15.5 amplification in colorectal cancer.结直肠癌中的Ascl2与11p15.5扩增

Gut. 2011 Nov;60(11):1606-7; author reply 1607. doi: 10.1136/gut.2010.231746. Epub 2010 Nov 23.

Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain.结直肠癌肝转移中 11p15.5 获得与 ASCL2 相关的干细胞标志和 IGF2 的表达。

Gut. 2010 Sep;59(9):1236-44. doi: 10.1136/gut.2009.195701. Epub 2010 May 17.

Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia.achaete-scute 样 2（ascl2）是 Wnt 信号通路的一个靶点，在肠道肿瘤中上调。

Oncogene. 2006 Jun 8;25(24):3445-57. doi: 10.1038/sj.onc.1209382. Epub 2006 Mar 27.

SEMA3F prevents metastasis of colorectal cancer by PI3K-AKT-dependent down-regulation of the ASCL2-CXCR4 axis.SEMA3F 通过下调 ASCL2-CXCR4 轴抑制结直肠癌细胞转移。

J Pathol. 2015 Aug;236(4):467-78. doi: 10.1002/path.4541. Epub 2015 May 22.

Rearrangements at the 11p15 locus and overexpression of insulin-like growth factor-II gene in sporadic adrenocortical tumors.散发性肾上腺皮质肿瘤中11p15位点的重排及胰岛素样生长因子-II基因的过表达。

J Clin Endocrinol Metab. 1994 Jun;78(6):1444-53. doi: 10.1210/jcem.78.6.7911125.

Entopic overexpression of Ascl2 does not accelerate tumourigenesis in ApcMin mice.Ascl2 的过表达并不会加速 ApcMin 小鼠的肿瘤发生。

Gut. 2012 Oct;61(10):1435-8. doi: 10.1136/gutjnl-2011-300842. Epub 2011 Dec 3.

Differential expression patterns of the insulin-like growth factor 2 gene in human colorectal cancer.胰岛素样生长因子2基因在人类结直肠癌中的差异表达模式

Tumour Biol. 2004 Jan-Apr;25(1-2):62-8. doi: 10.1159/000077725.

HIF-1α/Ascl2/miR-200b regulatory feedback circuit modulated the epithelial-mesenchymal transition (EMT) in colorectal cancer cells.缺氧诱导因子-1α/无翅型MMTV整合位点家族成员2/微小RNA-200b调节反馈回路调控结肠癌细胞的上皮-间质转化

Exp Cell Res. 2017 Nov 15;360(2):243-256. doi: 10.1016/j.yexcr.2017.09.014. Epub 2017 Sep 9.

Elevated expression of ASCL2 is an independent prognostic indicator in lung squamous cell carcinoma.ASCL2表达升高是肺鳞状细胞癌的独立预后指标。

J Clin Pathol. 2016 Apr;69(4):313-8. doi: 10.1136/jclinpath-2015-203025. Epub 2015 Oct 19.

Expression of insulin-like growth factor-2 can predict the prognosis of human colorectal cancer patients: correlation with tumor progression, proliferative activity and survival.胰岛素样生长因子-2的表达可预测人类结直肠癌患者的预后：与肿瘤进展、增殖活性和生存的相关性

Oncology. 1998 May-Jun;55(3):242-8. doi: 10.1159/000011858.

引用本文的文献

ASCL2 induces an immune excluded microenvironment by activating cancer-associated fibroblasts in microsatellite stable colorectal cancer.ASCL2 通过激活微卫星稳定结直肠癌中的癌症相关成纤维细胞，诱导免疫排斥的微环境。

Oncogene. 2023 Sep;42(38):2841-2853. doi: 10.1038/s41388-023-02806-3. Epub 2023 Aug 17.

Genetic and epigenetic basis of hepatoblastoma diversity.肝癌多样性的遗传和表观遗传基础。

Nat Commun. 2021 Sep 20;12(1):5423. doi: 10.1038/s41467-021-25430-9.

R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells.R-spondin1/Wnt 增强的 Ascl2 自我调控控制结直肠癌细胞祖细胞的自我更新。

Cell Cycle. 2018;17(8):1014-1025. doi: 10.1080/15384101.2018.1469874. Epub 2018 Jun 25.

Small cell lung cancer tumors and preclinical models display heterogeneity of neuroendocrine phenotypes.小细胞肺癌肿瘤和临床前模型表现出神经内分泌表型的异质性。

Transl Lung Cancer Res. 2018 Feb;7(1):32-49. doi: 10.21037/tlcr.2018.02.02.

Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.YAP1/KLF5对Ascl2的激活确保了结肠癌祖细胞的自我更新能力。

Oncotarget. 2017 Nov 27;8(65):109301-109318. doi: 10.18632/oncotarget.22673. eCollection 2017 Dec 12.

Elevated ASCL2 expression in breast cancer is associated with the poor prognosis of patients.乳腺癌中ASCL2表达升高与患者预后不良相关。

Am J Cancer Res. 2017 Apr 1;7(4):955-961. eCollection 2017.

Elevated ASCL2 expression is associated with metastasis of osteosarcoma and predicts poor prognosis of the patients.ASCL2表达升高与骨肉瘤转移相关，并预示患者预后不良。

Am J Cancer Res. 2016 Jun 1;6(6):1431-40. eCollection 2016.

Achaete scute-like 2 suppresses CDX2 expression and inhibits intestinal neoplastic epithelial cell differentiation.无翅型基因同源物2抑制CDX2表达并抑制肠道肿瘤上皮细胞分化。

Oncotarget. 2015 Oct 13;6(31):30993-1006. doi: 10.18632/oncotarget.5206.

MicroRNA-200 (miR-200) cluster regulation by achaete scute-like 2 (Ascl2): impact on the epithelial-mesenchymal transition in colon cancer cells.achaete scute样蛋白2（Ascl2）对MicroRNA-200（miR-200）簇的调控：对结肠癌细胞上皮-间质转化的影响

J Biol Chem. 2014 Dec 26;289(52):36101-15. doi: 10.1074/jbc.M114.598383. Epub 2014 Nov 4.

Comprehensive molecular characterization of human colon and rectal cancer.全面的人类结肠和直肠癌分子特征分析。

Nature. 2012 Jul 18;487(7407):330-7. doi: 10.1038/nature11252.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验