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梗死后植入心脏复律除颤器进行二级预防患者的精神病理学。一项横断面、病例对照研究。

Psychopathology in postinfarction patients implanted with cardioverter-defibrillators for secondary prevention. A cross-sectional, case-controlled study.

机构信息

Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK.

出版信息

J Psychosom Res. 2010 Dec;69(6):555-63. doi: 10.1016/j.jpsychores.2010.06.002. Epub 2010 Aug 10.

DOI:10.1016/j.jpsychores.2010.06.002
PMID:21109043
Abstract

OBJECTIVE

To determine (1) the incidence of anxiety and depression in patients implanted with defibrillators for secondary arrhythmia protection after myocardial infarction; (2) the effect of comorbidity and receipt of shock therapy on psychosocial maladjustment.

METHODS

Cross-sectional, one-off, questionnaire-based (HADS; MOS SF-36), case-controlled study of defibrillator recipients (n=100) from a 3-year implant period and three groups of matched controls [pacemaker (n=50), coronary intervention (n=50), atrial fibrillation (n=50)], sharing specific preselected previous health experiences. Spouses of each subgroup (n=106) were also studied. Although a cardiac rehabilitation program was available routinely for postinfarction patients, no specific rehabilitation was provided after defibrillator or pacemaker implant.

RESULTS

Mean scores for each assessment were similar for each group. Individual patient scores, however, revealed similarly high incidences of anxiety (24-34%) and depression (14-22%) in all groups. Experience of implantable cardioverter-defibrillator (ICD) 'shock(s)' and 'shock storm(s)' (≥ 3 shocks in 24 h) increased anxiety significantly. HADS criteria for anxiety 'caseness' or borderline 'caseness' were met in 63.6% of shock-storm recipients. Abnormal anxiety scores did not differ with interval from index event. Individual HADS scores also identified high incidences of anxiety in all spouse groups (25-48%).

CONCLUSIONS

Experience of shock storm precipitates pathological levels of anxiety in ICD recipients, and need for an ICD contributes to spouse anxiety. Individual CBT is indicated for patients who experience multiple shocks along with psycho-education for spouses. Anxiolytic and antidepressant medications may be indicated as part of their psychological rehabilitation.

摘要

目的

确定(1)心梗后植入心律转复除颤器以预防心律失常的患者中焦虑和抑郁的发生率;(2)合并症和电击治疗对心理社会适应不良的影响。

方法

采用横断面、一次性问卷调查(HADS;MOS SF-36),对 3 年植入期内的心律转复除颤器受者(n=100)和 3 组匹配对照者[起搏器(n=50)、冠状动脉介入(n=50)、心房颤动(n=50)]进行病例对照研究,这些对照者均有特定的预先选择的既往健康史。还研究了各亚组的配偶(n=106)。虽然常规为心梗后患者提供心脏康复计划,但在植入心律转复除颤器或起搏器后,没有提供特定的康复。

结果

各评估的平均评分在各组之间相似。然而,个体患者的评分显示,所有组中焦虑(24-34%)和抑郁(14-22%)的发生率同样较高。植入式心脏转复除颤器(ICD)“电击(s)”和“电击风暴(s)”(24 小时内≥3 次电击)的经历显著增加了焦虑。符合 ICD 电击风暴患者中焦虑“病例”或“边缘病例”的 HADS 标准占 63.6%。焦虑异常评分与从指数事件的间隔时间无关。个别 HADS 评分也在所有配偶组中识别出较高的焦虑发生率(25-48%)。

结论

电击风暴的经历使 ICD 受者出现病理性焦虑水平,而 ICD 的需求导致配偶出现焦虑。对于经历多次电击的患者,需要进行个体认知行为治疗,同时对配偶进行心理教育。对于配偶,可以考虑使用抗焦虑和抗抑郁药物作为其心理康复的一部分。

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