Bässler K H
Physiologisch-chemisches Institut, Johannes Gutenberg-Universität Mainz.
Infusionstherapie. 1990 Feb;17(1):19-23.
Parenteral nutrition is incomplete without vitamins. Marginal vitamin deficiency under parenteral nutrition is certainly more common than generally recognized. Even marginal and undiscernable vitamin deficiency interferes with healing processes and increases the rate of complications since vitamins are involved in a variety of ways in wound healing, regeneration processes and immune function. If total parenteral nutrition is necessary for longer periods of time, exceeding 5 days, vitamins should be substituted in the recommended doses. The assessment of a marginal vitamin deficiency is difficult to perform and extremely expensive. It is therefore easier, safer and cheaper to substitute vitamins in total parenteral nutrition from the beginning, if preceeding malnutrition is likely. Recommendations for dosage and mode of application are reported and explained.
肠外营养中没有维生素是不完整的。肠外营养状态下的边缘性维生素缺乏肯定比普遍认为的更为常见。即使是边缘性且难以察觉的维生素缺乏也会干扰愈合过程并增加并发症发生率,因为维生素以多种方式参与伤口愈合、再生过程和免疫功能。如果需要长时间(超过5天)进行全肠外营养,应按推荐剂量补充维生素。评估边缘性维生素缺乏很难进行且成本极高。因此,如果患者之前可能存在营养不良,从一开始就在全肠外营养中补充维生素会更简单、更安全且更便宜。文中报告并解释了维生素的剂量和应用方式建议。