Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Science, Suzhou, 21513, P. R. China.
Chem Commun (Camb). 2011 Jan 28;47(4):1190-2. doi: 10.1039/c0cc04291a. Epub 2010 Nov 26.
A weak polyelectrolyte coating, carboxylated poly(oligo(ethylene glycol)methacrylate-co-2-hydroxyethylmethacrylate), was prepared via surface initiated polymerization (SIP) from initiators immobilized to gold surface through the Au-S bonds. When dry thickness increased up to 75 nm, this polyelectrolyte coating was pulled off the Au substrate by simply exposing to phosphate buffer saline (PBS, pH = 7.4, [Na(+)] = 150 mM). This covalent bond breaking (CBB) behavior was monitored in situ using a quartz crystal microbalance (QCM) and CBB was associated with the swelling of the anchored polyelectrolyte chains.
通过金表面通过 Au-S 键固定的引发剂引发的表面引发聚合（SIP），制备了弱聚电解质涂层，即羧基化聚（低聚乙二醇甲基丙烯酸酯-co-2-羟乙基甲基丙烯酸酯）。当干燥厚度增加到 75nm 时，通过简单地将其暴露于磷酸盐缓冲盐水（PBS，pH=7.4，[Na（+）]=150mM）中，即可将该聚电解质涂层从 Au 基底上拉下。使用石英晶体微天平（QCM）原位监测这种共价键断裂（CBB）行为，并且将 CBB 与锚固的聚电解质链的溶胀相关联。
