Department of Veterans Affairs, Health Services Research & Development, 2215 Fuller Road, (152), Ann Arbor, MI 48105, USA.
Drug Alcohol Depend. 2011 May 1;115(1-2):51-6. doi: 10.1016/j.drugalcdep.2010.10.007. Epub 2010 Dec 15.
The U.S. prevalence of misuse of prescription opioid analgesics has increased substantially over the past decade but research on the factors influencing misuse of these medications remains preliminary. In the literature on alcohol, marijuana and stimulants, substance-related expectancies have been found to predict level of substance use. A similar line of research is needed to better understand reasons for misusing pain medications.
This study utilized a sample of adults presenting to a large residential addictions treatment program (N=351). Participants were administered a new instrument, the Pain Medication Expectancy Questionnaire (PMEQ) as well as questions about current alcohol, illegal drug and pain medication misuse. Exploratory factor analysis was used to determine underlying factors of the PMEQ.
Results of the factor analysis supported a three-factor solution focusing on pleasure/social enhancement, pain reduction and negative experience reduction. In general, greater perceived expectancy of the positive effects of Prescription Opiate Analgesics (POAs) in all three domains were correlated with greater frequency of substance use and poorer mental health functioning. Expectancies directly related to the pain-reducing properties of POAs were also related to greater pain and poorer physical functioning.
This new measure of pain medication expectancies had sound psychometric properties and the resulting factors were associated with other clinically important aspects of patient functioning. The results highlight the need to assess for and address perceptions related to pain medication use in patients presenting to addictions treatment.
在过去的十年中,美国处方类阿片类药物滥用的流行率大幅上升,但关于影响这些药物滥用的因素的研究仍处于初步阶段。在关于酒精、大麻和兴奋剂的文献中,物质相关的预期被发现可以预测物质使用的水平。需要类似的研究来更好地理解滥用止痛药的原因。
本研究利用了一个向大型住院成瘾治疗项目(N=351)就诊的成年人样本。参与者接受了一种新的工具,即疼痛药物期望问卷(PMEQ),以及关于当前酒精、非法药物和疼痛药物滥用的问题。探索性因素分析用于确定 PMEQ 的潜在因素。
因素分析的结果支持了一个三因素的解决方案,重点是愉悦/社交增强、疼痛减轻和负面体验减轻。一般来说,在所有三个领域对处方阿片类镇痛药(POA)的积极影响的感知期望越高,物质使用的频率越高,心理健康功能越差。与 POA 减轻疼痛的特性直接相关的期望也与更大的疼痛和更差的身体功能有关。
这种新的疼痛药物期望测量具有良好的心理测量学特性,得出的因素与患者治疗中其他临床重要方面的功能有关。结果强调了在向成瘾治疗就诊的患者中评估和解决与疼痛药物使用相关的感知的必要性。