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自然感染后猪圆环病毒 2 型(PCV2)的脱落和感染动态。

Shedding and infection dynamics of porcine circovirus type 2 (PCV2) after natural exposure.

机构信息

Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, 1600 S. 16th Street, Ames, IA 50011, USA.

出版信息

Vet Microbiol. 2011 Apr 21;149(1-2):225-9. doi: 10.1016/j.vetmic.2010.10.021. Epub 2010 Nov 4.

Abstract

The objective of this study was to determine the amount of porcine circovirus type 2 (PCV2) shed in nasal, oral and fecal secretions over time following natural PCV2 infection. Fecal, oral and nasal swabs and blood were collected at regular intervals starting at 28 days post-farrowing (DPF) until 209 DPF from four pigs naturally infected with PCV2. PCV2 DNA was detected in all sample types. There were no differences in the amount of PCV2 DNA present in different sample types over time. PCV2 DNA was detectable in sera and secretions in pigs through 209 DPF. Natural exposure to PCV2 results in a long term infection and PCV2 is shed in similar amounts by nasal, oral and fecal routes.

摘要

本研究旨在确定猪圆环病毒 2 型(PCV2)在自然感染 PCV2 后随时间从鼻腔、口腔和粪便分泌物中排出的量。从产仔后 28 天(DPF)开始,每隔一段时间采集 4 头自然感染 PCV2 的猪的粪便、口腔和鼻腔拭子以及血液,直到 209 DPF。所有样本类型均检测到 PCV2 DNA。随着时间的推移,不同样本类型中 PCV2 DNA 的含量没有差异。PCV2 DNA 可在血清和分泌物中通过 209 DPF 检测到。自然接触 PCV2 会导致长期感染,并且 PCV2 通过鼻腔、口腔和粪便途径以相似的量排出。

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