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传输拉曼光谱在药物分析中应用的最新进展。

Recent advances in the application of transmission Raman spectroscopy to pharmaceutical analysis.

机构信息

Central Laser Facility, Research Complex at Harwell, Science and Technology Facilities Council, Rutherford Appleton Laboratory, Didcot, Oxfordshire OX110QX, UK.

出版信息

J Pharm Biomed Anal. 2011 Jun 25;55(4):645-52. doi: 10.1016/j.jpba.2010.10.029. Epub 2010 Nov 9.

Abstract

This article reviews recent advances in transmission Raman spectroscopy and its applications, from the perspective of pharmaceutical analysis. The emerging concepts enable rapid non-invasive volumetric analysis of pharmaceutical formulations and could lead to many important applications in pharmaceutical settings, including quantitative bulk analysis of intact pharmaceutical tablets and capsules in quality and process control.

摘要

本文从药物分析的角度综述了传输拉曼光谱及其应用的最新进展。这些新兴概念能够实现药物制剂的快速非侵入性体积分析,并可能在药物领域得到广泛应用,包括对完整的药物片剂和胶囊进行质量和过程控制的定量批量分析。

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