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Cotransplantation of umbilical cord MSCs to enhance engraftment of hematopoietic stem cells in patients with severe aplastic anemia.

作者信息

Chao Y-H, Tsai C, Peng C-T, Wu H-P, Chan C-K, Weng T, Wu K-H

出版信息

Bone Marrow Transplant. 2011 Oct;46(10):1391-2. doi: 10.1038/bmt.2010.305. Epub 2010 Nov 29.

DOI:10.1038/bmt.2010.305
PMID:21113191
Abstract
摘要

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Cotransplantation of umbilical cord MSCs to enhance engraftment of hematopoietic stem cells in patients with severe aplastic anemia.脐带来源间充质干细胞共移植以提高重型再生障碍性贫血患者造血干细胞的植入率。
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No Synergistic Effect of Cotransplantation of MSC and Ex Vivo TPO-Expanded CD34(+) Cord Blood Cells on Platelet Recovery and Bone Marrow Engraftment in NOD SCID Mice.在NOD SCID小鼠中,间充质干细胞(MSC)与体外血小板生成素(TPO)扩增的CD34(+)脐血细胞共移植对血小板恢复和骨髓植入无协同作用。
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Cotransplantation of ex vivo expanded and unexpanded cord blood units in immunodeficient mice using insulin growth factor binding protein-2-augmented mesenchymal cell cocultures.使用胰岛素样生长因子结合蛋白-2 增强的间充质细胞共培养物,在免疫缺陷小鼠中进行体外扩增和未扩增脐带血细胞的共移植。
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Cotransplantation of haploidentical hematopoietic and umbilical cord mesenchymal stem cells with a myeloablative regimen for refractory/relapsed hematologic malignancy.采用清髓性方案将单倍体造血和脐带间充质干细胞共移植治疗难治/复发性血液系统恶性肿瘤。
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Stem Cells Cloning. 2024 Dec 5;17:41-58. doi: 10.2147/SCCAA.S481072. eCollection 2024.
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Mesenchymal Stem Cells in Acquired Aplastic Anemia: The Spectrum from Basic to Clinical Utility.获得性再生障碍性贫血中的间充质干细胞:从基础到临床应用的范围。
Int J Mol Sci. 2023 Feb 24;24(5):4464. doi: 10.3390/ijms24054464.
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Alterations of mesenchymal stem cells on regulating Th17 and Treg differentiation in severe aplastic anemia.
骨髓增生异常综合征中骨髓间充质干细胞对 Th17/Treg 分化的调控作用。
Aging (Albany NY). 2023 Jan 30;15(2):553-566. doi: 10.18632/aging.204500.
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Therapeutic Perspectives for the Clinical Application of Umbilical Cord Hematopoietic and Mesenchymal Stem Cells: Overcoming Complications Arising After Allogeneic Hematopoietic Stem Cell Transplantation.脐带血造血和间充质干细胞的临床应用治疗展望:克服异基因造血干细胞移植后的并发症。
Adv Exp Med Biol. 2023;1409:111-126. doi: 10.1007/5584_2022_726.
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Int J Mol Sci. 2022 Jul 25;23(15):8196. doi: 10.3390/ijms23158196.
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Dose-dependent benefits of iron-magnetic nanoparticle-coated human umbilical-derived mesenchymal stem cell treatment in rat intracranial hemorrhage model.铁磁纳米颗粒包被的人脐带间充质干细胞治疗对大鼠颅内出血模型的剂量依赖性获益。
Stem Cell Res Ther. 2022 Jun 21;13(1):265. doi: 10.1186/s13287-022-02939-4.
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Int J Mol Sci. 2022 May 10;23(10):5295. doi: 10.3390/ijms23105295.
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