Department of Clinical and Social Dentistry, Federal University of Paraiba, João Pessoa, Brazil.
Oral Dis. 2011 May;17(4):420-6. doi: 10.1111/j.1601-0825.2010.01770.x. Epub 2010 Nov 29.
Is there a relationship between enamel defects and early childhood caries?
A total of 275 children participated in a cohort study from birth to 54 months of age. Enamel defects were determined by the development defects enamel index and dental caries was registered according to the WHO criteria. Data were analyzed using descriptive, analytical techniques, multivariate analysis, and evidence-based tools as number needed to harm (NNH).
In the follow up, 224 children were still in the study, 81.3% presented at least one tooth with enamel defect and 44.2% had dental caries. An association was found between enamel defects and dental caries (P = 0.0091). Multivariate analysis showed that night bottle-feeding, absence of fluoride and enamel defects were predictors of dental caries at 18 months (P < 0.05). Enamel defect was the only statistically significant variable to influence the development of caries at 24, 30, 36, and 42 months. At 48 months, the use of fluoride toothpaste had effect on the decrease of caries (P < 0.05). The NNH for enamel defects in relation to dental caries was 3.0, at 24 months and 5.0 at 54 months.
Enamel defect is a predisposing factor for ECC.
牙釉质发育不全与幼儿龋病之间是否存在关系？
共有 275 名儿童参与了一项从出生到 54 个月的队列研究。牙釉质发育不全通过发育缺陷牙釉质指数来确定，而龋齿则根据世界卫生组织的标准进行登记。使用描述性、分析性技术、多变量分析和基于证据的工具（如需要治疗的人数，NNH）来分析数据。
在随访中，仍有 224 名儿童参与了研究，81.3%的儿童至少有一颗牙齿存在牙釉质发育不全，44.2%的儿童患有龋齿。牙釉质发育不全与龋齿之间存在关联（P=0.0091）。多变量分析表明，夜间奶瓶喂养、氟化物缺失和牙釉质发育不全是 18 个月时龋齿的预测因素（P<0.05）。牙釉质发育不全是唯一对 24、30、36 和 42 个月时龋齿发展有统计学显著影响的变量。48 个月时，使用含氟牙膏对减少龋齿有影响（P<0.05）。牙釉质发育不全与龋齿相关的 NNH 为 3.0，在 24 个月时，5.0 在 54 个月时。
牙釉质发育不全是幼儿龋病的一个易感因素。
