采用新方法估计全国范围内基于医院的 HIV 血清流行率；2002-2008 年在韩国。
Estimation of hospital-based HIV seroprevalence as a nationwide scale by novel method; 2002-2008 in Korea.
机构信息
Division of AIDS, Korea Centers for Disease Control and Prevention, Seoul, Korea.
出版信息
BMC Public Health. 2010 Nov 30;10:739. doi: 10.1186/1471-2458-10-739.
BACKGROUND
In Korea, approximately 70% of HIV-positive individuals are currently diagnosed in hospitals, while most HIV-positive patients were diagnosed at public health centers in 1980 s and 1990 s. However, there are no reporting systems to identify how many HIV tests are performed in the Korean hospitals different from public health centers and Blood centers. We estimated how many HIV tests were performed in hospitals and analyzed the nationwide hospital-based HIV seroprevalence in the present study.
METHODS
Between 2002 and 2008, data included HIV tests on insurance claims in hospitals and the proportion of computerized insurance claims from the Health Insurance Review and Assessment Services. The number of HIV tests from the survey in the External Quality Assurance Scheme for hospital laboratories was collected to calculate the insurance claim proportion. HIV seroprevalence was estimated using data of tested individuals, including infected individuals. Statistical analysis was confirmed with the 95% confidence interval. Statistical significance was defined at p-values < 0.05.
RESULTS
The number of HIV tests in hospitals increased from 2.7 million in 2002 to 5.0 million in 2008. The trend of HIV seroprevalence was decrease (1.5-1.3 per 10,000 individuals, P < 0.0028), except in 2002. The number of women tested was greater than men, and the proportion increased in older individuals and in small towns. Men had a higher annual HIV seroprevalence than women (P < 0.0001). The annual seroprevalence decreased in men (P = 0.0037), but was stable in women. The seroprevalence in the 30-39 year age group demonstrated higher than other age groups except 2008.
CONCLUSIONS
The nationwide hospital-based number of HIV tests and seroprevalence were estimated using a new method and seroprevalence trends were identified. This information will facilitate improvement in national HIV prevention strategies.
背景
在韩国，目前约有 70%的 HIV 阳性个体是在医院确诊的，而大多数 HIV 阳性患者是在 20 世纪 80 年代和 90 年代在公共卫生中心确诊的。然而，目前还没有报告系统可以确定在韩国的医院和血站进行了多少 HIV 检测。本研究旨在估计医院进行的 HIV 检测数量，并分析全国范围内基于医院的 HIV 血清流行率。
方法
在 2002 年至 2008 年期间，数据包括医院的保险索赔中的 HIV 检测以及健康保险审查和评估服务的计算机化保险索赔比例。通过收集医院实验室外部质量保证计划的调查中 HIV 检测数量，计算保险索赔比例。使用包括感染者在内的受检个体的数据来估计 HIV 血清流行率。使用 95%置信区间确认统计分析。定义 P 值 < 0.05 为具有统计学意义。
结果
医院的 HIV 检测数量从 2002 年的 270 万增加到 2008 年的 500 万。HIV 血清流行率的趋势是下降（每 10000 人 1.5-1.3，P < 0.0028），除 2002 年外。接受检测的女性人数多于男性，且在年龄较大的人群和小城镇中比例增加。男性的年度 HIV 血清流行率高于女性（P < 0.0001）。男性的年度血清流行率下降（P = 0.0037），而女性则保持稳定。除 2008 年外，30-39 岁年龄组的流行率高于其他年龄组。
结论
使用新方法估计了全国范围内基于医院的 HIV 检测数量和血清流行率，并确定了血清流行率趋势。这些信息将有助于改善国家的 HIV 预防策略。
Zotero 插件