Dept. of Pathology and Anatomical Sciences, University at Buffalo, Buffalo, NY, USA.
J Sport Rehabil. 2010 Nov;19(4):399-410. doi: 10.1123/jsr.19.4.399.
High-voltage pulsed current (HVPC), a form of electrical stimulation, is known to curb edema formation in laboratory animals and is commonly applied for ankle sprains, but the clinical effects remain undocumented.
To determine whether, as an adjunct to routine acute and subacute care, subsensory HVPC applied nearly continuously for the first 72 h after lateral ankle sprains affected time lost to injury.
Multicenter, randomized, double-blind, placebo-controlled trial.
Data were collected at 9 colleges and universities and 1 professional training site.
50 intercollegiate and professional athletes.
Near-continuous live or placebo HVPC for 72 h postinjury in addition to routine acute and subacute care.
Time lost to injury measured from time of injury until declared fit to play.
Overall, time lost to injury was not different between treated and control groups (P = .55). However, grade of injury was a significant factor. Time lost to injury after grade I lateral ankle sprains was greater for athletes receiving live HVPC than for those receiving placebo HVPC (P = .049), but no differences were found between groups for grade II sprains (P = .079).
Application of subsensory HVPC had no clinically meaningful effect on return to play after lateral ankle sprain.
高压脉冲电流（HVPC）是一种电刺激形式，已知可抑制实验动物的水肿形成，常用于治疗踝关节扭伤，但临床效果仍未记录。
确定在常规急性和亚急性治疗的基础上，在外侧踝关节扭伤后最初的 72 小时内近乎连续应用亚阈 HVPC 是否会影响因伤损失的时间。
多中心、随机、双盲、安慰剂对照试验。
在 9 所学院和 1 个专业培训点收集数据。
50 名校际和职业运动员。
在常规急性和亚急性治疗的基础上，在受伤后 72 小时内进行近乎连续的活 HVPC 或安慰剂 HVPC。
从受伤时间到宣布适合参赛的因伤损失时间。
总体而言，治疗组和对照组之间因伤损失的时间没有差异（P =.55）。然而，损伤程度是一个显著因素。接受活 HVPC 的运动员的 I 级外侧踝关节扭伤后的因伤损失时间大于接受安慰剂 HVPC 的运动员（P =.049），但 II 级扭伤的两组间无差异（P =.079）。
亚阈 HVPC 的应用对外侧踝关节扭伤后重返赛场没有明显的临床意义。
