Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.
Aging Clin Exp Res. 2010 Aug;22(4):330-9. doi: 10.1007/BF03324937.
In advanced age, the influence of vertebral fractures on quality of life extends well beyond the usual sequelae of osteoporosis. In order to intercept older subjects' distress associated with the clinical, functional, social and psychological consequences of the disease, we developed and validated a multidimensional instrument (the triple-Q questionnaire) tailored to older women with osteoporotic fractures. We also examined specific aspects of the questionnaire correlated with bone mineral density.
100 osteoporotic women with vertebral fractures and 100 controls aged >65 years, underwent a thorough examination, which also included X-ray of the thoraco-lumbar spine, hip densitometry, the triple-Q questionnaire, and five referral instruments evaluating function, cognition, perception of general health, mood and pain.
The questionnaire was repeatable and able to discriminate between older women with and without vertebral fractures. There was a strong association between referral instrument scores and the corresponding single domain score of the questionnaire. Femoral BMD was also associated with scores indicating fear of falling, fear of fracture, and pain.
The questionnaire intercepted the influence of osteoporosis on the quality of life of elderly women with vertebral fractures. Subjects who suffered from severe pain and were more fearful of falling were most likely to be severely osteoporotic.
在高龄人群中，椎体骨折对生活质量的影响远远超出了骨质疏松症的常见后遗症。为了减轻与疾病的临床、功能、社会和心理后果相关的老年患者的痛苦，我们开发并验证了一种多维工具（三重-Q 问卷），专门针对患有骨质疏松性骨折的老年女性。我们还研究了与骨密度相关的问卷的特定方面。
100 名患有椎体骨折的骨质疏松女性和 100 名年龄>65 岁的对照者接受了全面检查，其中包括胸腰椎 X 射线、髋部骨密度测定、三重-Q 问卷以及五个评估功能、认知、一般健康感知、情绪和疼痛的转诊工具。
问卷具有可重复性，能够区分有和无椎体骨折的老年女性。转诊工具的评分与问卷相应的单一域评分之间存在很强的关联。股骨 BMD 也与跌倒恐惧、骨折恐惧和疼痛评分相关。
问卷截获了骨质疏松症对患有椎体骨折的老年女性生活质量的影响。患有严重疼痛和更害怕跌倒的患者最有可能患有严重的骨质疏松症。
