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关节镜治疗股骨髋臼撞击症后异位骨化:NSAID 预防的作用。

Heterotopic ossifications after arthroscopic management of femoroacetabular impingement: the role of NSAID prophylaxis.

机构信息

Policlinico San Donato, P.zza Malan, 2, 20097, San Donato Milanese, Milan, Italy.

出版信息

J Orthop Traumatol. 2010 Dec;11(4):245-50. doi: 10.1007/s10195-010-0121-z. Epub 2010 Nov 30.

DOI:10.1007/s10195-010-0121-z
PMID:21116673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3014465/
Abstract

BACKGROUND

open hip surgery is known to be a risk for heterotopic ossification (HO), and nonsteroidal anti-inflammatory drugs (NSAIDs) have been widely recognized as an effective prevention. Hip arthroscopy is gaining popularity thanks to the possibility of treating femoroacetabular impingement (FAI) with a minimally invasive technique, however little is known about its rate of postoperative HO. The aim of the present study is to evaluate HO prevalence after hip arthroscopy for FAI and its relationship with NSAID prophylaxis.

MATERIALS AND METHODS

we retrospectively reviewed 300 FAI cases who have been managed with hip arthroscopy in two different hospitals from April 2006 to May 2009. All medical records and indications at discharge were analyzed, focusing on administration of NSAIDs, as well as follow-up roentgenograms with regard to presence of HO around the hip joint. The patients were divided into two groups: a treatment group of 285 hips which received NSAID prophylaxis and a control group of 15 hips which did not.

RESULTS

five hips presented HO, with overall prevalence of 1.6%. All five patients with HO belonged to the control group. No HO was observed in the treatment group. Thus, HO rate turned out to be significantly higher (P < 0.001) in patients who did not receive NSAIDs after surgery.

CONCLUSION

arthroscopic treatment of FAI is not exempt from potential development of HO. NSAIDs after arthroscopic FAI treatment seem to be an effective prevention.

摘要

背景

开放性髋关节手术已知存在异位骨化(HO)的风险,而非甾体抗炎药(NSAIDs)已被广泛认为是一种有效的预防措施。髋关节镜检查由于能够以微创技术治疗股骨髋臼撞击症(FAI)而越来越受欢迎,但是对于其术后 HO 的发生率知之甚少。本研究的目的是评估髋关节镜治疗 FAI 后 HO 的发生率及其与 NSAID 预防的关系。

材料和方法

我们回顾性分析了 2006 年 4 月至 2009 年 5 月在两家不同医院接受髋关节镜治疗的 300 例 FAI 病例。分析了所有病历和出院时的指征,重点关注 NSAIDs 的使用情况,以及随访髋关节周围 HO 的 X 线片。将患者分为两组:接受 NSAID 预防治疗的 285 髋治疗组和未接受 NSAID 预防治疗的 15 髋对照组。

结果

5 髋出现 HO,总发生率为 1.6%。所有 5 例 HO 患者均来自对照组。治疗组未观察到 HO。因此,未接受 NSAIDs 治疗的患者术后 HO 发生率明显更高(P<0.001)。

结论

FAI 的关节镜治疗并不能免除 HO 的潜在发生。髋关节镜 FAI 治疗后使用 NSAIDs 似乎是一种有效的预防措施。

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