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年龄相关性黄斑变性与玻璃体后脱离的存在

Age related macular degeneration and presence of posterior vitreous detachment.

作者信息

Gawecki Maciej, Doroszkiewicz Mariusz, Rydzewski Jacek

机构信息

Department of Ophthalmology, Specialist Hospital, Chojnice.

出版信息

Klin Oczna. 2010;112(7-9):210-2.

PMID:21117364
Abstract

PURPOSE

To find correlation between presence of PVD and incidence of different forms of AMD.

MATERIAL AND METHODS

210 eyes of patients with AMD were examined. Fluorescein angiography determined type of AMD and ultrasound examination evaluated presence of PVD. Control group included 164 eyes of patients routinely admitted to the hospital for cataract surgery. Inclusion criterium was lack of AMD and retinal medical history.

RESULTS

In the control group prevalence of PVD was higher in women than in men--respectively 50.5% and 23.6%. PVD was more frequent in male patients with dry AMD (50%) than in male controls (23.6%). PVD was also more frequent in female patients with dry form of AMD (69.2%) than in controls (50.5%). In female group with AMD PVD was more frequent in patients with dry form of AMD than in patients with wet form of AMD (69.2% and 44.8%). In patients with dry AMD, PVD was statistically more frequent in women (69.2%) than in men (50%). Statistically significant was the difference between prevalence of PVD in dry and wet group (male and females together)--60.7% in dry AM and 42.6% ind wet AMD.

CONCLUSION

Persistence of vitreal adhesion and traction with age might lead to a shift of the dry form into wet form of AMD. Detachment of the vitreous in dry AMD might secure the persistence of dry form. Women, due to early PVD are more prone to complications resulting from vitreoretinal traction.

摘要

目的

探究玻璃体后脱离(PVD)的存在与不同类型年龄相关性黄斑变性(AMD)发病率之间的关联。

材料与方法

对210例AMD患者的眼睛进行检查。荧光素血管造影确定AMD的类型,超声检查评估PVD的存在情况。对照组包括164例因白内障手术常规入院患者的眼睛。纳入标准为无AMD及视网膜病史。

结果

对照组中,女性PVD的患病率高于男性,分别为50.5%和23.6%。干性AMD男性患者中PVD的发生率(50%)高于男性对照组(23.6%)。干性AMD女性患者中PVD的发生率(69.2%)也高于对照组女性(50.5%)。在AMD女性组中,干性AMD患者的PVD发生率高于湿性AMD患者(69.2%和44.8%)。在干性AMD患者中,女性PVD的发生率(69.2%)在统计学上高于男性(50%)。干性和湿性AMD组(男性和女性合并)PVD患病率之间的差异具有统计学意义,干性AMD为60.7%,湿性AMD为42.6%。

结论

随着年龄增长,玻璃体粘连和牵引的持续存在可能导致AMD从干性转变为湿性。干性AMD中玻璃体脱离可能使干性形式得以持续。由于女性较早发生PVD,更容易出现玻璃体视网膜牵引导致的并发症。

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